肾功能检查英文课件.pptVIP

Kidney diseaseLaboratory examinationsunflower Kidney function Generation urine Drain water, metabolites, waste and keep useful material Regulating water and osmotic pressure Regulating electrolyte and acid-base balance Make some important physiological active substances, such as renin, EPO. The first sectionglomerularFunction testing Glomerular filtration rate (GFR) is reflected glomerular filtration function objective index, with unit time two renal generated ultrafiltrate quantity namely former urine generation to said Renal clearance is refers to the double kidney in unit time (min) inside, can how much ml plasma contains a substance to clear all, results to ml/min or L / 24 h 1. The endogenous creatinine clearance 1. The endogenous creatinine clearance 1. The endogenous creatinine clearance The preparation for the patient The patient continuous eating low protein food 3 days, every protein intake 40 g, fast meat, forbidden to drink strong tea, coffee, avoid strenuous exercise Specimen collection(标本收集) The fourth day morning 8 start collecting 24 hour urine (join toluene anticorrosive), the blood in any time 2 ml and urine (measurement of urine volume) at the same time cleared Calculation formula（计算公式） Every minute creatinine clearance = urine creatinine concentration × every minute urine volume/plasma creatinine concentration (unit: ml/min) Normal Range Adult :80-120 ml/min Neonatal :40 ~ 65 ml/min Increased in and decreased in. Page278 Clinical significance 1. Are early reflect glomerular filtration function of the sensitive index.(the majority of acute glomerulonephritis Ccr low to normal below 80%, but serum BUN, Cr is still in the normal range) 2. Preliminary appraisal renal damage 70 ~ 51 ml/min mild damage 50 ~ 31 ml/min moderate damage 30 ml/min severe damage Chronic renal failure patients Ccr if: 20 ~ 11 ml/min early renal failure 10 ~ 6 ml/min advanced renal failure 5 ml/min end-stage renal failure 3. Guide therapy