不同免疫方式对仔猪免疫高致病性猪繁殖与呼吸_省略_合征_猪瘟_猪口蹄疫三种疫苗抗.pdfVIP

中国动物传染病学报 2014,22(5): 61-67 Chinese Journal of Animal Infectious Diseases ·简报· 不同免疫方式对仔猪免疫高致病性猪繁殖与呼吸综 合征、猪瘟、猪口蹄疫三种疫苗抗体水平的影响 胡 杰，张步娴，屈素洁，莫胜兰，粟艳琼，陆文俊，施开创，李 军 （广西动物疫病预防控制中心，南宁530001） 摘 要：采用不同的免疫方式，对38头36 ～38 日龄健康仔猪进行高致病性猪繁殖与呼吸综合征、猪瘟、猪口蹄疫3种疫苗进行免 疫，分别于免疫前（0 d ）和免疫后15、30、45 、60、90 d采血进行这3种疫病抗体检测。结果发现效果最好的方法是先免疫猪 瘟和口蹄疫疫苗14 d后再免疫高致病性猪繁殖与呼吸综合征疫苗；其次是猪瘟疫苗和高致病性猪繁殖与呼吸综合征疫苗分别释 稀后混合为1针，口蹄疫疫苗另作1针同时分点注射；免疫效果最差的是高致病性猪繁殖与呼吸综合征、猪瘟、猪口蹄疫3种疫 苗同时分3点注射。 关键词：免疫程序；高致病性猪繁殖与呼吸综合征；猪瘟；猪口蹄疫；抗体 中图分类号：S852.659.6 文献标志码：B 文章编号：1674-6422 （2014 ）05-0061-07 EFFECT OF DIFFERENT VACCINATION PROTOCOLS ON ANTIBODY LEVELS OF HIGHLY PATHOGENIC PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME, CLASSICAL SWINE FEVER AND FOOT AND MOUTH DISEASE VACCINES IN PIGLETS HU Jie, ZHANG Bu-xian, QU Su-jie, MO Sheng-lan, SU Yan-qiong, LU Wen-jun, SHI Kai-chuang, LI Jun (Guangxi Animal Disease Prevention and Control Center, Nanning 530001, China) Abstract: Different vaccination protocols were taken to vaccinate thirty-eight 36-38-day-old healthy piglets with highly pathogenic porcine reproductive and respiratory syndrome (HP-PRRS), classical swine fever (CSF) and foot and mouth disease (FMD) vaccines, respectively. The antibody levels of CSFV, FMDV and PRRSV were tested on day 0, 15, 30, 45, 60 and 90 post vaccination. The highest antibody levels were detected when CSF and FMD vaccines were used fi rst followed by HP-PRRS vaccine 14 days later. The second choice was that CSF and HP-PRRS vaccines were mixed in one shot on one side of piglets and at the same time FMD vaccine was used on other side. The lowest antibody levels were detected when HP-PRRS, FMD and CSF vaccines were injected at the same time at three separate shots. Key words: Vaccination protocol; highly pathogenic por