基因组学技术在致病基因发现.pptVIP

结果与讨论 —— miRNA差异比较 Higher Lower Fold Change 5-10 10-50 50 RS4;11 Jurkat, GM mir-320b, mir-1292, mir-222, mir-195, let-7c, mir-122, mir-1277-3p, mir-671-5p mir-125b, mir-519d, mir-3666, mir-148b mir-199b-3p, mir-4458, mir-30a Jurkat RS4;11, GM mir-223, mir-1278, mir-95, mir-9, let-7b mir-766, mir-181d, mir-92b, mir-363 NA GM RS4;11, Jurkat mir-193b, mir-223*, mir-146b-5p mir-138-5p, mir-21, mir-15b-5p mir-193b*, mir-155 miRNA显著上调比较 miRNA表达上下调分析 RS4;11 Exp. Jurkat Exp. GM Exp. mir-422a 8.27 mir-140-3p 8.57 mir-3927 1.64 mir-423-5p 6.98 mir-29c-3p 1.96 mir-320b 6.45 特异性高表达miRNA Lower expression