模拟退火-支持向量机在sle合并肾受累的辅助诊断应用研究.docVIP

模拟退火-支持向量机在SLE合并肾受累的辅助诊断应用研究 王曦 张果 付萍 王剑平 杨晓洪 欧阳鑫 昆明理工大学信息工程与自动化学院 昆明医科大学第二附属医院风湿免疫科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 建立一种计算机辅助诊断 (CAD) 模型对系统性红斑狼疮 (SLE) 合并肾受累进行分类辅助诊断, 为及时发现并确诊该疾病提供一种新的方法。方法 利用模拟退火 (SA) 算法优化支持向量机 (SVM) 算法惩罚系数C和核函数参数g, 并基于此构建SA-SVM分类器模型, 将其应用于SLE的智能辅助诊断。结果 该方法避免了单一SVM分类器易陷入局部最优的缺点, 提高了分类器的分类精度, 且针对SLE合并肾受累疾病的分类准确率最高可达98.72%。结论 实验结果表明该分类模型在SLE合并肾受累疾病智能诊断中有较好的应用价值。 关键词： 支持向量机; 模拟退火; 人工智能; 诊断设备; 系统性红斑狼疮并发肾受累; 作者简介：王曦, 女, 硕士研究生, 研究方向:数据挖掘与分类研究, E-mail:962255481@ 作者简介：张果;E-mail:guo_zh1119@163.com; 作者简介：付萍, E-mail:1756047267@ 收稿日期：2017-04-20 基金：国家自然科学基金资助项目 Applicability of SA-SVM classifier to auxiliary diagnosis of renal involvement in SLE WANG Xi ZHANG Guo FU Ping WANG Jian-ping YANG Xiao-hong OU Yang-xin Faculty of Information Engineering and Automation, Kunming University of Science and Technology; Department of Rheumatic Immunity, Second Affiliated Hospital, Kunming Medical University; Abstract： Objective To establish a computer-aided diagnosis ( CAD) model for the classification and diagnosis of systemic lupus erythematosus ( SLE) complicated with renal involvement, and to provide a new method for the timely detection and diagnosis of the disease. Methods Simulated annealing ( SA) algorithm was used to optimize the penalty coefficient C and kernel function parameter g of the support vector machines ( SVM) algorithm before an SA-SVM classifier model was established and was applied to the intelligent assistant diagnosis of SLE. Results Unlike the single SVM classifier, this method never fell into local optimum, and improved the classification accuracy of a classifier. The classification accuracy for SLE with renal involvement was as high as 98. 72%. Conclusion The experimental results show that this classification model is well applicable to the intelligent diagnosis of SLE with renal involvement. Keyword： support vector machines; simulated annealing algorithm; artificial intel