脐血干细胞与创面修复.pdfVIP

986 · · 现代生物医学进展 Progress in Modern Biomedicine Vol.11 NO.5 MAR.2011 脐血干细胞与创面修复 罗 瞳 李利平 （南华大学附属第一医院烧伤整形外科湖南衡阳421001） 摘要：脐血干细胞是一类具有多向分化潜能的原始祖细胞，具备自我更新和增殖的能力，在特定条件诱导下可以分化为不同细 胞，逐渐作为临床组织工程的来源细胞。近年来随着对脐血干细胞的不断研究，发现其在创面修复中具有明显的优势，成为创面 临床治疗的一条新途径。本文从脐血干细胞的生物学特性、采集与冻存、体外扩增等方面对创面修复的研究进行综述。 关键词：脐血干细胞 创面修复 扩增 R813 R62 A 1673-6273 2011 05-986-03 中图分类号： 文献标识码： 文章编号： （ ） Umbilical cord blood stem cell and wound repair LUO Tong, LI Li-p ing (Dept .of Burns and p lastic Surgery , The 1st Affiliated Hosp ital, Nanhua University, Hengyang, Hunan 42 100 1, China ) ABSTRACT: Umbilical cord blood stem cells is a class of multi-differentiation potential of primitive progenitor cells, with the ability of self-renewal and proliferation, under certain conditions can be induced to differentiate into different cells, and gradually as the source of cells in clinical tissue engineering.In recent years, with the continuously research in umbilical cord blood stem cells, it has obvious superiority in the wound repair, and has become a new way of wound clinical treatment. This article will simply review the research in wound repair from umbilical cord blood stem cell biology, collection and freeze-stored, amplification in vitro etc. Keywords: Umbilical cord blood stem cells; Wound repair; Amplification Chinese Library Classification(CLC): R813 R62 Document code: A Article ID:1673-6273(2011)05-986-03 CD34 如何有效的对创面进行修复（如大面积烧伤、创伤、糖尿 系分化为外胚层的神经细胞，内胚层的肝细胞。 分子是一 病、褥疮等造成的皮肤正常组织结构和完整性的破坏而形成的 种跨膜的唾液黏蛋白一直被视为干细胞的标志，脐血中CD34+ 创面）是目前创面临床治疗的难点。脐血干细胞是一类具有与