先天性心脏病英文稿2009版.ppt

Congenital Heart Disease,(CHD) 先天性心脏病 The first affiliated hospital of the SUN YAT-SEN university Prof. Wang Huishen 王慧深 huishenwang@ Outline 教学大纲——目的要求： 了解：胎儿及生后循环解剖及血流动力学改变； 熟悉：先天性心脏病的病因、分类及各类型特点； 熟悉：先天性心脏病的诊断方法； 掌握：ASD、VSD、PDA、TOF的血流动力学， 临床特点和诊断要点； 熟悉：上述几种常见先心病的治疗原则。 Scientific medicine begins Cardiac Catheterization Early Open Heart Surgery With Heart-Lung Machine C.Dennis 1952 2/2 Died J.Gibbon 1953 5/6 Died J.Helmsworth 1953 1/1 Died D.Dodrill 1953 2/2 Died G.Clowes 1953 2/2 Died W.Mustard 1953/54 5/5 Died 17/18 94.5% Died Jacqueline Noonan (1921-) Genetics of Noonan syndrome Noonan Syndrome Noonan JA. Hypertelorism with Turner phenotype. Am J Dis Child.1968;116:373-380 New Advances (in moderm times) Cardiac Imaging: (development quick) Echocardiography Cardiac MRI/CT Cardiac Intervention (Cath lab) Heart Failure: Medications Biventricular Pacemaker (synchronization) Heart Transplantation/Surgery (assist devices) Gene Therapy … Catalogs Normal cardiovascular physiological and dissection CHD general introduction Cardiovascular diseases examination methods in children Atrial septal defect（ASD） Ventricular septal defec（VSD） Patent Ductus Arteriosus（PDA） Tetralogy of Fallot（TOF） Definition CHD : the maldevelopment of heart and great vessels to cause abnormalities when the embryo period The Cardiovascular formation Embryo development of the heart Cardiac development Cardiac development Gases and nutritional requirements exchange occurs in the placenta Pulmonary blood flow is very low Foramen ovale and ductus arteriosus are opened The blood saturation is higher in up limbs and head Close of the circulation in infant after birth Foramen ovale(PFO) —— Functional close: after birth ——Anatomically close: 5~7 months Ductus arterios