5-氨基酸酮戊光动力学疗法在预防尿道尖锐湿疣术术后复发中的意义.docVIP

精品论文 参考文献 5-氨基酸酮戊光动力学疗法在预防尿道尖锐湿疣术术后复发中的意义 蔡锦楠 陈松波 吴华红 　　（汕头市中心医院皮肤科 515031） 　　【摘要】目的 探讨5-氨基酸酮戊光动力学疗法（ALA-PDL）在预防尿道尖锐湿疣术术后复发中的意义。方法　将我院收治的100例确诊为尿道尖锐湿疣患者按照入院时间随机分为对照组（单独电灼治疗）和治疗组（ALA-PDL联合电灼治疗），对比观察两组患者的复发率以及不良反应。结果　治疗组的复发率（9.3%）明显低于对照组（36%），治疗组的不良反应发生率（8%）明显低于对照组（56%），差异对比均具有统计学意义（Plt;0.05）。结论　ALA-PDL联合电灼治疗尿道CA的疗效显著，术后复发率较低，不良反应较少，是一种安全、有效的治疗方法。 　　【关键词】 5-氨基酸酮戊光动力学疗法 尖锐湿疣 术后复发 效果 　　【中图分类号】R51 【文献标识码】A 【文章编号】2095-1752（2014）09-0058-02 　　 　　Meaning of photodynamic therapy of 5-ketone amino acids in prevention of postoperative recurrence of urethra condyloma acuminatum operation 　　Cai Jinnan Chen Songbo, Wu Huahong. Department ofdermatology, Central hospital of Shantou Guangdong, Shantou. 515031 　　【Abstract】 Objective：To study meaning of photodynamic therapy of 5-ketone amino acids in prevention of postoperative recurrence of urethra condyloma acuminatum operation. Methods：100 patients diagnosed as urethral condyloma acuminatum in our hospital were randomly divided into control group (electric bright treatment alone) and treatment group (ALA-PDL with electric bright therapy), according to admission time. Recurrence rate and adverse reaction of patients of two groups were comparated and observed.Results：Recurrence rate (9.3%) of treatment group was obviously lower than the control group (36%), and the incidence of adverse reactions (8%) of treatment group was obviously lower than the control group (56%).Contrast differences were statistically significant (P lt; 0.05). Conclusion：Curative effect of ALA-PDL combined with fulguration for the treatment of urethral CA is distinct, and its postoperative recurrence rate is low. It has less adverse reaction, and is a safe and effective treatment method. 　　【Key words】 photodynamic therapy of 5-ketone amino acids urethra condyloma acuminatum postoperative recurrence effect 　　尖锐湿疣（CA）是目前国内外发病率最高的性传播疾病之一，主要是由于感染了人类乳头瘤病毒（HPV）所致，临床治疗CA的方法具有多样性，传统的治疗方法包括激光、高频电离子、