86例临床新诊断2型糖尿病患者短期胰岛素强化与降糖药物治疗对胰岛C肽值变化临床观察.docVIP

精品论文 参考文献 86例临床新诊断2型糖尿病患者短期胰岛素强化与降糖药物治疗对胰岛C肽值变化临床观察 张俊杰 　　（临沂战友医院内科? 山东 临沂 276000） 　　【摘要】 目的：观察探析临床新诊断糖尿病患者短期胰岛素强化治疗前后C肽值变化的临床观察。 方法：我科室在近期收治的86例新诊断糖尿病患者，分成两组，一组运用口服降糖药，另一组胰岛素强化治疗。C肽释放实验，口服标准馒头餐或75g无水水葡萄糖。 胰岛素强化治疗C肽值恢复有效率97.67%明显高于口服降糖药组88.37%（p〈0.05）。在各项相关指标方面比较，胰岛素短期强化治疗均比口服药物明显改善胰腺B细胞功能。组间比较胰岛素组优于口服药组（Plt;0.05）。结论：初步临床诊断2型糖尿病患者短期胰岛素强化治疗对C肽恢复优于口服降糖药物治疗。 　　【关键词】新临床诊断2型糖尿病；胰岛素强化治疗 C肽值；胰腺B细胞功能恢复 　　【中图分类号】R587.1 【文献标识码】A 【文章编号】2095-1752（2015）24-0038-02 　　86 cases of clinical patients with newly diagnosed type 2 diabetes short-term insulin strengthening and hypoglycemic drug treatment clinical observation to islet c-peptide values change 　　Zhang Junjie. Linyi Comrades Hospital, Shandong Province, Linyi 276000, China 　　【Abstract】 Objective Observation analysis clinical patients with newly diagnosed diabetes of short-term insulin intensive treatment before and after the clinical observation of c-peptide values change. Methods My department in the records of 86 patients with newly diagnosed diabetes recently, divided into two groups, a group of using oral medications, another group of insulin intensive therapy. C peptide release experiment, oral standard steamed bread or 75 g glucose without water. Insulin intensive treatment significantly better than C peptide recovery efficiency 97.67% oral medications group 88.37% (p lt; 0.05). Results In terms of the related indexes, short-term insulin intensive therapy than oral medications significantly improve the function of pancreatic B cells. Insulin group is better than that of oral medications is compared between group (P lt; 0.05). Conclusions Preliminary clinical diagnosis of short-term insulin intensive therapy in patients with type 2 diabetes of C peptide recovery is better than that of oral hypoglycemic drugs. 　　【Key words】 The new clinical diagnosis of type 2 diabetes; Insulin intensive therapy; C peptide value; Pancreatic B cells function recovery 　　新诊断2型糖尿病患者，糖化血红蛋白大于9的。口干，多饮多尿临