不孕患者体外受精胞浆内单精子注射妊娠结局的回顾性分析.docVIP

精品论文 参考文献 不孕患者体外受精胞浆内单精子注射妊娠结局的回顾性分析 游焱球1 邓小云2 温丽萍1 (1广东省韶关市妇幼保健院生殖科 512026) (2韶关市粤北人民医院 广东韶关 512026) 【摘要】目的 探讨不孕患者应用体外受精/胞浆内单精子注射（IVF/ICSI）妊娠结局的回顾特点。方法　本次选取100例接受IVF/ICSI助孕的不孕患者作研究对象，分析影响妊娠结局的因素。结果　本次选择的100例不孕患者，年龄le;30岁50例，31-35岁40例，ge;36岁10例。妊娠率分别为56%，47.5%，40%。总妊娠率为51%。显示随年龄增加，妊娠率呈下降趋势，年龄le;30岁妊娠率明显高于其它两组（Plt;0.05）。继发不孕54例，原发不孕46例，前者妊娠率为51.8%，50%，组间比较无明显差异（Pgt;0.05）。卵巢功能低下占1%，排卵巢障碍占5%，输卵管因素占85%，其它因素占9%。非条件logistic回归分析显示，针对妊娠结局，HCG日P值，用药方案，BMI为危险因素（beta;gt;0，ORgt;1），而内膜厚度、即往妊娠史、总优胚数、M2卵泡数为保护因素（beta;lt;0，ORlt;1）。超排方案中，短方案组10例，长方案组90例，妊娠率分别为30%，70%，差异有统计学意义（Plt;0.05）。结论　影响IVF/ICSI妊娠结局的因素较多，针对不孕接受IVF/ICSI助孕治疗的患者，获得成功妊娠为多因素共同作用结果，需建立个体化治疗方案，防范不良因素，以提高妊娠成功率，满足不孕患者的生育需求。 【关键词】不孕 体外受精 胞浆内单精子注射 妊娠结局 回顾 【中图分类号】R3 【文献标识码】A 【文章编号】2095-1752（2014）07-0019-02 A retrospective analysis of the infertile patients IVF / intracytoplasmic sperm injection pregnancy outcome 【Abstract】Objective: To investigate the characteristics of sperm injection Review (IVF / ICSI) in the infertile patients with IVF / ICSI pregnancy outcome. Methods: The 100 patients to receive IVF / ICSI progesterone infertility patients for the study, analysis of factors affecting the outcome of pregnancy. Result: The selected 100 cases of infertility patients, aged le; 30 years old 50 cases 40 cases ,31-35 years, ge; 36 years of age in 10 cases. Pregnancy rates were 56%, 47.5%, 40%. The total pregnancy rate was 51%. Show with increasing age, pregnancy declined, age le; 30 years of age pregnancy rate was significantly higher than the other two groups (P lt;0.05). Secondary infertility in 54 cases, 46 cases of primary infertility, pregnancy former 51.8%, 50%, no significant difference (Pgt; 0.05) between the two groups. 1% of ovarian dysfunction, ranked ovarian disorders accounted for 5%, 85% tubal factor, other factors accounted for 9%. Unconditional logistic regression analysis showed that for the p