原发性中度高血压患者血压晨峰与心肌重塑的相关性研究.docVIP

精品论文 参考文献 原发性中度高血压患者血压晨峰与心肌重塑的相关性研究 达军 肖丽塔 　　（博尔塔拉蒙古自治州人民医院心内科 新疆 博乐 833400） 　　【摘要】 目的：分析和探讨原发性中度高血压患者血压晨峰（MBS）与心肌重塑的相关性。方法：选取我院2012年2月—2013年2月收治的130例原发性中度高血压患者，对其进行24h动态血压监测，其中存在血压晨峰现象患者65例作为观察组，无血压晨峰65例患者作为对照组，应用超声心动仪对两组患者临床指标进行监测分析。结果：观察组患者LAD、LVDd、IVS、LVPWT、晨峰血压、BNP、hs-CRP水平较对照组更高，左心室肥厚较对照组更明显（Plt;0.05）。结论：存在血压晨峰的原发性中度高血压患者左心室心肌肥厚比不存在血压晨峰患者更明显，BNP、hs-CRP水平明显升高，可见血压晨峰与心肌重塑现象密切相关。 　　【关键词】 原发性中度高血压；血??晨峰；心肌重塑 　　【中图分类号】R544.1 【文献标识码】A 【文章编号】2095-1752（2015）23-0024-02 　　Correlation between morning blood pressure surge and cardiac remodeling in patients with essential hypertension 　　Da Jun, Xiao Tana.Department of Cardiology, People s Hospital of BortalaMongolia Autonomous Prefecture, Xinjiang, Bole833400 China 　　【Abstract】Objective To investigate the correlation between morning blood pressure surge (MBS) and myocardial remodeling in patients with essential hypertension. Methods Select our hospital , no morning blood pressure peak of 65 cases of patients as the control group, ultrasound echocardiography instrument of two groups of patients with clinical indicators for monitoring and analysis. Results The levels of LAD,, LVDd, IVS, LVPWT, morning blood pressure, hs-CRP and BNP were higher in the observation group than in the control group, and left ventricular hypertrophy was more obvious than the control group (Plt;0.05). Conclusion There morning blood pressure peak of primary of moderate hypertension patients with left ventricular hypertrophy is more obvious than there is no morning blood pressure surge in patients, the levels of BNP and hs CRP increased significantly, visible morning blood pressure surge and myocardial remodeling are closely related. 　　【Key words】Essential hypertension; Morning blood pressure surge; Cardiac remodeling 　　近年来，临床心脑血管疾病发生率不断上升，如冠心病、高血压、心肌缺血等，且清晨及上午时段发病率较高，血压晨峰（MBS）是高血压临床研究的重点[1]。血压晨峰与靶器官损害的严重程度、心血管并发症存在明显关系，那么血压晨峰与心肌重塑是否有关？本文分析2012年2月～2013年2月我院收治的130例原发性中度高血压患者临床资料，研究血压晨峰与心肌重塑的相关性，现报道如下。 　　1.资料与方