双时相18F-FDG-CT在肺腺癌临床诊断中的价值.docVIP

精品论文 参考文献 双时相18F-FDG-CT在肺腺癌临床诊断中的价值 1江西南昌大学附属赣州医院 江西 赣州 341000 2赣南医学院第一附属医院 江西 赣州 341000) 作者简介：田云生，男，1972年9月出生，副主任医师，研究方面：肺部恶性肿瘤 [摘要]目的：探讨双时相18F-FDG-PET/CT在肺腺癌临床诊断中的应用价值。方法：筛选2015年1月至2016年4月我院收治的疑似肺腺癌但CT、磁共振等检查不能提供明确诊断依据的患者40例为研究对象。患者均表现为血清CEA指标不同程度升高，行全身双时相18F-FDG-PET/CT检查，并与患者手术活检病理学诊断结果以及随访6个月结果进行比较，研究双时相18F-FDG-PET/CT检查在肺腺癌临床诊断中的应用价值。结果：40例疑似肺腺癌患者中发现核素异常浓聚35例，手术病理证实33例为肺腺癌，5例疑似患者无核素浓聚，随访调查结果显示1例患者为高分化肺腺癌，因而双时相18F-FDG-PET/CT检查对肺腺癌的诊断灵敏度为97.16%(33/34)，特异性为71.43%(5/7)，准确性为92.50%(37/40)，阳性预测值为94.29%(33/35)，阴性预测值为80.00%(4/5)。结论：双时相18F-FDG-PET/CT在肺腺癌的临床诊断中具有较高的敏感性与特异性，在早期肺腺癌诊断以及预后评估中均具有重要的临床应用价值。 【中图分类号】R994.1【文献标识码】A【文章编号】1001-5213(2016)08-0288-01 关键词：双时相18F-FDG-PET/CT检查；肺腺癌；临床诊断；应用价值 [abstract] objective: to study the two-phase 18 f - FDG PET/CT in the diagnosis of lung adenocarcinoma clinical application value. Methods: between January 2015 and April 2016 our hospital suspected lung adenocarcinoma but does not provide clear diagnosis based on CT or mri 40 cases of patients as the research object. Patients were characterized by higher serum CEA index to varying degrees, did the two-phase 18 f - FDG PET/CT examination, and patients with surgical biopsy pathology diagnosis and follow-up of 6 months result comparison, study the two-phase 18 f - FDG PET/CT examination in the diagnosis of lung adenocarcinoma clinical application value. Results: 40 patients with suspected pulmonary adenocarcinoma were found abnormal nuclide concentration in 35 cases, surgical pathology confirmed 33 cases of lung adenocarcinoma, 5 cases of suspected patients without nuclide concentration, follow-up survey in 1 case for well-differentiated lung adenocarcinoma patients, and therefore the two-phase 18 f - FDG PET/CT examination in the diagnosis of lung adenocarcinoma sensitivity was 97.16% (33/34), specificity of 71.43% (5/7), accuracy was 92.50% (37/40), positive predictive value was 94.29% (33/35), negative predictive value was 80.00% (4/5). Conclusion: when the two-phase 18 f - FDG