吉林省长春市成年人群连续三年慢性肾脏病流行病学分析.docVIP

精品论文 参考文献 吉林省长春市成年人群连续三年慢性肾脏病流行病学分析 李银辉　武仁　刘宝玲　王晶　刘水仙 一汽总医院(吉林大学第四医院)　吉林　长春　１３００１１ 基金项目:吉林省自然科学基金项目(２０１２１５０８６) 　　【摘要】　目的　探讨吉林省长春市成年人群连续三年慢性肾脏病(CKD)的患病情况和相关危险因素.方法　连续三年通过对吉林省长春市成年人群进行CKD及相关危险因素的问卷调查(既往史、吸烟、饮酒等)、体格检查(血压、身高和体重质量)和肾脏相关检测(尿微量白蛋白/肌酐比值;尿常规及沉渣;血清肌酐;并估算肾小球滤过率).同时还进行危险因素相关检测包括血糖;血尿酸;血脂水平检测.了解吉林省长春市成年人群CKD的患病情况及相关危险因素. 结果　三年分别３２６８例、３００２例、３１３３例资料完整的人群中,CKD的患病率分别为１５．４％、１２．６％、１６．９％.多因素Logistic回归提示,年龄、高血压、高尿酸、高血脂和高体质量指数是CKD独立危险因素.结论　吉林省长春市城市成年人群中,CKD的患病率较高,相关危险因素包括年龄、高血压、高血脂、高尿酸、高体质量指数. 【关键词】　肾疾病;患病率;横断面筛查;流行病学EpidemiologicAnalysisofChronicKidneyDiseaseinAdultPopulationinChangchunCity,JilinProvinceForThreeConsecutiveYears　LIYinhuiWU RenLIU Baoling WANGJingLIUShuixianFAW GeneralHospital (TheFourth HospitalofJilinUniversity),ChangchunJilin１３００１１,China【Abstract】ObjectiveToanalysistheprevalenceandriskfactorsofchronickidneydisease(CKD)inAdultPopulationinChangchunCity,JilinProvinceForthreeconsecutiveyearsMethodsQuestionnaire(anamnesis,smoking,drink)ofriskfactorsofCKD ;PhysicalExamination (bloodpressure,heightandbodymass);Kidneyrelatedtesting(uromicroprotein/creatinineratio;urineandsediment;serumcreatinine;andtoestimateglomerularfiltrationrate)．Detectionofriskfactorsincludingbloodsugar,blooduricacidbloodlipid．Throughstatisticalanalysis,toanalysistheprevalenceandriskfactorsofCKDinAdultPopulationinChangchunCity,JilinProvinceForthreeconsecutiveyears．．ResultsInthreeconsecutiveyears,Eligibledataof３２６８,３００２,３１３３subjectswereenrolledinthestudy．TheprevalenceofCKDrespectivelywas１５．４％、１２．６％、１６．９％,IndependentriskfactorsofCKDwereage,hypertension,highuricacid,highcholesterolandhighBMI．ConclusionsTheprevalenceofCKDisquitehighinAdultPopulationinChangchunCity,JilinProvince．RiskfactorsofCKDwereage,hypertenＧsion,【hKiegyhwuorircdsa】cid,highcholesterolandhighBMI． Kidneydiseases;Prevalence;Cross－sectionalstudy;Epidemiology 【中图分类号】R２４１．２ 【文献标识码】B 　　【文章编号】１００８－６３１５(２０１５)１２－１２４９－０２　　 　　近年来全球慢性肾脏病(CKD)的发生率逐年上升,尤其是终末期肾病(ESRD)所致的沉重医疗负担,使CKD 防治成为共同关注的公共卫生问题[１－２].近１０余年来,美国等发达国家的全国性调查显示成年人群中CKD的患病率