三种免疫策略下水痘流行病学特征分析.docVIP

三种免疫策略下水痘流行病学特征分析 黄振水 苗壮 秦爱玲 淄博市疾病预防控制中心 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 分析淄博市高新区三种水痘疫苗免疫策略的流行病学特征变化。方法 选取2007-2016年传染病报告信息管理系统报告的现住淄博市高新区水痘病例, 采用描述流行病学方法对不同水痘免疫策略的水痘流行病学特征及发病率、构成比进行分析。结果 自费期、免1期、免2期年均发病率分别为31.29/10万、35.27/10万、20.44/10万, 免2期较免1期、自费期冬春季发病高峰均有削弱, 15岁小年龄组人群水痘病例构成比逐渐下降, 15岁人群发病构成比呈上升趋势, 地区发病率逐渐下降。免2期与免1期相比, 4岁年龄别发病率、构成比较1岁下降更明显。结论 高水平水痘疫苗接种率可降低适龄儿童水痘发病率, 2剂次水痘免疫策略效果更好。 关键词： 水痘; 免疫策略; 流行特征; 作者简介：黄振水 (1976-) , 男, 硕士, 主管医师, 研究方向:免疫规划管理 收稿日期：2017-06-30 Epidemiological characteristics of varicella under three immunization strategies HUANG Zhen-shui MIAO Zhuang QIN Ai-ling Zibo Center for Disease Control and Prevention; Abstract： Objective To analyze the epidemiological characteristics under three immune strategies of varicella vaccine in high-tech zone of Zibo city. Methods The varicella cases were selected in high-tech zone of zibo city from a report information management system of infectious diseases in 2007-2016, and descriptive epidemiological methods were adopted to analyze epidemiological characteristics, incidence and composition of varicella under difference immunization strategies. Results During the self-paid period ( 2007-2009) , free 1-dose period ( 2010-2012) and free 2-dose period ( 2013-2016) , the annual average incidence rates were 31. 29, 35. 27, 20. 44 per 100000 population respectively. Compared with the self-paid period and free 1-dose period, the free 2-dose period disease peak of winter and spring were weakened. The proportions of cases under 15 years old decreased gradually while proportions of cases≥15 years old increased, and the incidence of disease in the region were gradually decreasing. Compared with the free 1-dose period, in the free 2-dose period age-specific incidence rate and a constituent ratio of 4 ~ decreased more significantly than 1 . Conclusion High-level varicella vaccination rate can reduce the incidence of varicella in school-age children, and the effe