妊娠合并血小板减少症患者输注血小板的疗效评估.docVIP

精品论文 参考文献 妊娠合并血小板减少症患者输注血小板的疗效评估 周攀1 张洪为2 　　（1泸州医学院附属医院检验科 四川泸州 646000） 　　（2泸州医学院附属医院输血科 四川泸州 646000） 　　【摘要】 目的：评估血小板输注对妊娠合并血小板减少患者的临床疗效。方法：病例为我院78例妊娠合并血小板减少症的住院患者，按照血小板计数分为两组，A组为20times;109/Llt;PLTlt;50times;109/L，B组为PLTlt;20times;109/L。两组患者均进行了血小板输注治疗。在输注前及输注后24小时检测患者血小板计数，计算血小板计数增加校正值和血小板回收率，评估两组患者血小板输注疗效。结果：与A组比较，B组的CCI和PPR明显增高(Plt;0.05)。结论：妊娠合并血小板减少患者输注血小板时应结合病情和血小板计数做出正确决定。 　　【关键词】妊娠合并血小板减少症；血小板；疗效；输血 　　【中图分类号】R714.25 【文献标识码】A 【文章编号】1007-8231（2015）18-0124-02 　　Evaluation of platelet transfusion in patients with Thrombocytopenia in pregnancy Zhou pan1, Zhang hong-wei2.1,Affiliated Hospital of Luzhou Medical College Department of laboratory medicine; 2,Affiliated Hospital of Luzhou Medical College department of blood transfusion 　　【Abstract】Objective To evaluate the clinical efficacy of platelet transfusion in patients with Thrombocytopenia in pregnancy. Methods 78 patients with thrombocytopenia in pregnancy were divided into group A (20times;109lt;PLTlt;50times;109)and group B(PLTlt;20times;109) according to the platelet count.Platelet counts were detected before and after 24 h after infusion.CCI(corrected count increment) and PPR(percentage platelet recovery) were calculted to evaluate the clinical efficacy of platelet transfusion. Results Compared with group B, the CCI and PPR were significantly higher in group A(Plt;0.05). Conclusion The correct decision should be combined with disease and platelet count when patients with thrombocytopenia in pregnancy were need to be infused platelet. 　　【Key words】Thrombocytopenia in pregnancy;Platelet; Curative effect; Blood transfusion 　　妊娠合并血小板减少症（Thrombocytopenia in pregnancy，PT）是目前产科较为常见的妊娠合并血液系统疾病，容易导致产妇产后出血，甚至是产妇脑出血及其他脏器出血，同时新生儿颅内出血几率也有所增加(麻醉风险和手术风险都明显增大，对于孕产妇及新生儿具有潜在危害[1]。妊娠期PLT减少的主要原因包括：妊娠相关性血小板减少症、妊娠高血压、特发性血小板减少性紫癜、巨幼红细胞性贫血、再生障碍性贫血、脾功能亢进以及原因不明的血小板减少[2]。血小板输注是提高机体血小板计数，促进止凝血功能的有效手段，目前还没有任何一种药物能够替代血小板的作用。但是，由于一些免疫因素和非免疫因素的影响，血小板存在输注无效的情况[3]。因此，本研究拟选择78例妊娠合并血小板减少症的住院患者，