尿道下裂术后谷氏祛腐生肌液尿道灌注冲洗的临床疗效分析.docVIP

精品论文 参考文献 尿道下裂术后谷氏祛腐生肌液尿道灌注冲洗的临床疗效分析 曹龙滨1 薛恩达1 李博2 孙茸1 谷万里1 　　【摘 要】 目的 观察尿道下裂术后谷氏祛腐生肌液经多孔硅胶双支架管行尿道灌注冲洗的临床疗效。方法 选择聊城市人民医院及聊城市第二人民医院小儿外科及泌尿外科2009.2-2015.3年住院治疗的212例尿道下裂患者，按照年龄及尿道下裂术式类型，均衡分为3组，治疗组1（70例）于尿道下裂术后，经多孔硅胶双支架管给予庆大霉素联合谷氏祛腐生肌液尿道灌注，治疗组2（71例）术后灌注冲洗庆大霉素，对照组（71例）灌注冲洗生理盐水，并对术后各组冲洗液浑浊情况、愈合情况、尿瘘并发症、术后6个月内尿道狭窄的发生情况，及无尿道狭窄并发症患者尿流率测定情况进行观察和记录。结果 治疗组1的70例患者中，发生尿漏4例，均于4周后瘘口自然闭合，尿道口狭窄4例，经尿道扩张后痊愈；治疗组2的71例患者中，发生漏尿5例，均于4周后瘘口自然闭合，尿道狭窄8例，5例经尿道扩张后痊愈，3例需择期行尿道成形术；治疗组3的71例患者中，发生漏尿8例，4例于4周后瘘口自然闭合，4例需二期行尿道瘘修补术，尿道口狭窄11例，5例经尿道扩张后痊愈，6例需择期行尿道成形术。治疗组1术后冲洗液浑浊情况较治疗组2及对照组明显为清。尿流率测定情况，治疗组1Qmax高于治疗组2及对照组。结论 治疗组1术后尿道瘘并发症与治疗组2无明显差别，但较对照组明显降低；尿道狭窄并发症发生率则明显低于治疗组2及对照组。谷氏祛腐生肌液经多孔硅胶双支架管行尿道灌注冲洗的临床疗效良好，较常规治疗可明显降低术后并发症，特别是尿道狭窄并发症的几率。 　　【关键词】 尿道下裂； 谷氏祛腐生肌液； 多孔硅胶双支架管； 尿道灌注冲洗； 尿流率 　　Analysis of clinical efficacy of flushing Gushi Qufushengji liquid urethral perfusion after hypospadias surgery CaoLongBin1 XueEnDa1 LiBo2 SunRong1 GuWanLi1*.1.Liaocheng Peoples Hospital 252000；2The second peoples Hospital of Liaocheng City 252600 　　【Abstract】 Objective To observe the after hypospadias repair Valleys Qu Shengji liquid the porous silica gel double stent tube urethral perfusion of the clinical efficacy. Methods 212 cases of hypospadias patients and pediatric department of Urology Second Hospital of Liaocheng Peoples Hospital and Liaocheng 2009.2-2015.3 hospital treatment, according to the age and hypospadias type, balanced and divided into 3 groups, treatment group 1 (70 cases) in hypospadias surgery by double stent porous silica gel tube given gentamycin combined with Gushi Qufushengji liquid urethral perfusion treatment group 2 (71 cases) perfusion of gentamicin after surgery, the control group (71 cases) perfusion of saline, and each group of washing liquid turbidity, postoperative healing, complications, postoperative urinary fistula occurred within 6 months after the urethral stricture were observed and recorded, and no complications of urethral stricture patients uroflometry case