Blumenfield Neurology Prefrontal Cortex And Long Term Memory Encoding An Integrative Review Of Findings From Neuropsychology And Neuroimaging英文电子书.pdf

Blumenfield Neurology Prefrontal Cortex And Long Term Memory Encoding An Integrative Review Of Findings From Neuropsychology And Neuroimaging英文电子书.pdf

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Prefrontal Cortex and Long-Term Memory Encoding: An Integrative Review of Findings from Neuropsychology and Neuroimaging ROBERT S. BLUMENFELD and CHARAN RANGANATH Center for Neuroscience and Department of Psychology, University of California at Davis Recent findings have led to a growing appreciation of the role of the lateral prefrontal cortex (PFC) in episodic long-term memory (LTM). Here, the authors will review results from neuropsychological and neu- roimaging studies of humans and present a framework to explain how different regions of the PFC con- tribute to successful LTM formation. Central to this framework is the idea that different regions within the PFC implement different control processes that augment memory by enhancing or attenuating memory for certain aspects of a particular item or event. Evidence reviewed here suggests that ventrolateral regions of the PFC contribute to the ability to select goal-relevant item information, and that this processing strength- ens the representation of goal-relevant features of items during LTM encoding. Dorsolateral regions of the PFC may contribute to the ability to organize multiple pieces of information in working memory, thereby enhancing memory for associations among items in LTM. Thus, dorsolateral and ventrolateral regions of the PFC may implement different control processes that support LTM formation in a complementary fashion. NEUROSCIENTIST 13(3):280–291, 2007. DOI: 10.1177/1073858407299290 KEY WORDS Working, Organization, Selection, Frontal, Lobes, Associative, Episodic, Memory Memorizing phone numbers, remembering past conversa- encoding and consider how our framework can help to tions, finding where you left your keys—these are the clarify the role of the PFC in LTM encoding. kinds of daily activities that depend on the ability to form coherent episodic memories. Recent res

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