清肝补肾方治疗老年脂肪肝的临床观察Clinical observation of Qinggan Bushen prescription in the treatment of senile fatty liver.pdfVIP

提 要 目的：观察清肝补肾方治疗老年脂肪肝的临床疗效，并探讨其作用机理。方法： 采用随机单盲对照的方法，将 60 例老年脂肪肝患者分为清肝补肾方治疗组和血脂康 胶囊对照组，每组各 30 例，两组在合理膳食、适量运动、并停用其他针对本病有治 疗作用药物的基础上，治疗组给予清肝补肾方治疗，对照组给予血脂康胶囊，用药3 个月后，进行疗效性评定，观察治疗前后主要症状体征、实验室检查肝功能（ALT、 AST、γ-GT）、血脂（TG、TC）、肝脏 B 超的影像学的改变以及安全性指标的观察。 结果：治疗组总的有效率为 86.7%，与对照组总有效率为 70%相比，具有显著性差异 （P0.05).同时治疗组的血脂、肝功、肝脏B超较治疗前明显改善。结论：清肝补肾 方能明显改善老年脂肪肝患者临床症状，改善血脂、肝功，提高患者生活质量，具有 重要的临床应用价值。 关键词 清肝补肾方；老年脂肪肝；临床观察 Clinical observation on Qing Gan Bu Shen Fang treating senile fatty liver Speciality:Medicine of TCM Tutor:Prof.Cui Dezhi Author:Wu Kaibang Abstract Objective: To observe the clinical efficacy of the Liver Kidney Treatment of senile fatty liver, and to explore its mechanism. Methods: randomized single blind controlled is divided into 60 cases of elderly patients with fatty liver Liver kidney treated group and Xuezhikang control group, 30 cases in each group, two groups at a reasonable diet, regular exercise, and stop give Liver kidney treatment of other medical therapies for this disease on the basis of the treatment group and control group was given Xuezhikang, three months after the drug efficacy assessment, observation and treatment before and after the main symptoms and signs, laboratory tests of liver function (ALT, AST, and of γ-GT), lipids (TG and TC), liver B-mode ultrasound imaging changes and observation of safety indicators. Results: The treatment group, the total effective rate was 86.7%, with the control group, the total effective rate compared to 70%, with significant differences (P 0.05). Treatment group, blood lipids, liver function, liver B super than before treatment was significantly improved. Conclusion