清胃降逆汤治疗胆汁反流性胃炎的临床研究Clinical study of Qingwei descending Decoction in the treatment of bile reflux gastritis.pdfVIP

提 要 目的：本课题主要探讨清胃降逆汤治疗胆汁反流性胃炎的临床疗效及作用机制， 为今后的临床应用提供可靠依据。 方法：随机分组，将 60 例胆汁反流性胃炎随机分成两组。试验组 30 例，给予 中药汤剂（清胃降逆汤）治疗；对照组 30 例，给予口服西药吗丁啉治疗。治疗期间 均不用其他治疗药物。观察两组患者治疗前后的症状疗效，舌脉变化和胃镜下胆汁反 流程度与胃粘膜相改变。 结果：试验组与对照组临床症状疗效分别为痊愈 53.33%、26.67%；显效 26.67%、 30.00%；有效 16.67%、16.67%；无效 3.33%、20.00%；总有效率 96.67%、73.33%。 两组总疗效比较 P0.05，有显著性差异，试验组临床症状疗效优于对照组。两组胃 镜检查疗效分别为痊愈 50.00%、26.67%；显效 33.33%、30.00%；有效 13.33%、23.33%； 无效 6.67%、20.00%；总有效率 93.33%、80.00%。两组总疗效对比 P0.05,有显著 性差异，试验组胃镜检查疗效优于对照组。 结论：清胃降逆汤能有效的改善胆汁反流性胃炎患者的临床症状，充分体现了中 医治疗胆汁反流性胃炎的优势，相比于西药治疗，具有疗效确切、安全、无毒副作用 的特点。 关键词 胆汁反流性胃炎；清胃降逆汤；吗丁啉；胃镜检查 Clinical research of Qingwei Jiangni Decoctionin the treatment of Bile reflux gastritis Speciality：Internal medicine of traditional Chinese medicine Author ：Zhang Zhihua Tutor：Prof. Liu Weiming Abstract Objective: This subject mainly explore that the Qingwei Jiangni decoction in the treatment of Bile reflux gastritis clinical curative effect and mechanism for future clinical application to provide reliable basis Methods: To 60 cases reverse flow of Bile reflux gastritis into two groups at random. 30 patients in the trial, give Native Chinese traditional medicine (Qingwei Jiangni Decoction) treatment ；30 patients in the control group, Give oral Domperidone to treatment. During treatment are not other drugs. Observe both groups of patients before and after treatment effect of the symptoms, Tongue pulse change and under the upper level and the bile flow gastric mucosal inflammation change. Results: Patients with clinical symptoms curative effect for the control group respectively cure53.33% 、26.67% ； powerfully26.67% 、30.00% ； effective 16.67% 、 16.67%；invalid 3.33%、20.00% ；total effective 96.67% 、73.33