阿司匹林联合氯吡格雷治疗急性脑梗死的临床效果.docVIP

阿司匹林联合氯吡格雷治疗急性脑梗死的临床效果 党卫军 蒋建华 宋昌军 李娟 陕西省森工医院神经内科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 探讨急性脑梗死治疗中应用阿司匹林联合氯吡格雷的临床效果。方法 将我院收治的120例急性脑梗死患者随机分成试验组与对照组, 每组60例。试验组患者给予阿司匹林联合氯吡格雷治疗;对照组单服拜阿司匹林。比较两组患者的缺血事件再发率, 治疗前、后的NIHSS评分与Barthel指数、hs-CRP水平及血小板聚集率。结果 试验组治疗后缺血事件再发率明显低于对照组, 差异具有统计学意义 (P0.05) ;治疗后, 两组患者的NIHSS评分与Barthel指数均优于治疗前, 且试验组上述指标评分明显优于对照组 (P0.05) ;治疗后, 两组患者的血浆hs-CRP水平和血小板聚集率均优于治疗前, 且试验组明显优于对照组 (P0.05) 。结论 阿司匹林联合氯吡格雷的治疗效果与安全性高于单服阿司匹林, 具有临床推广价值。 关键词： 急性脑梗死; 阿司匹林; 氯吡格雷; 作者简介：党卫军 (1979-) , 男, 汉族, 陕西商洛人, 主治医师。研究方向:神经内科疾病的诊断与治疗。 Clinical effect of aspirin combined with clopidogrel in the treatment of acute cerebral infarction DANG Wei-jun JIANG Jian-hua SONG Chang-jun LI Juan Department of Neurology, Shaanxi Sengong Hospital; Abstract： Objective To evaluate the clinical efficacy of aspirin combined with clopidogrel in the treatment of acute cerebral infarction. Methods One hundred and twenty acute cerebral infarction patients admitted in our hospital were ran-domly divided into control group and experimental group, with 30 cases in each group. The experimental group received aspirin combined with clopidogrel, and the control group received aspirin. The ischemic event recurrence rate, NIHSS score, Barthel index, hs-CRP level and platelet aggregation rate before and after treatment were compared between the two groups. Results The ischemic event recurrence rate of the experimental group were lower than that of the control group ( P0.05) . After treatment, the NIHSS scores and Barthel indexes were better than those before treatment, and those indexes scores above of the experimental group were better than the control group (P0.05) . After treatment, the hs-CRP levels and platelet aggregation rates were better than those before treatment, and those of the experimental group were better than the control group (P0.05) . Conclusion The efficacy and safety of aspirin combined with clopidogrel in the treatment of acute cerebra