新生儿缺氧缺血性脑病的临床治疗.docVIP

精品论文 参考文献 新生儿缺氧缺血性脑病的临床治疗 （成都市锦江区妇幼保健院 610000） 【摘要】 目的：探讨新生儿缺氧缺血性脑病的有效治疗方法。方法：纳入78例缺氧缺血性脑病患儿参与研究，并将78例患儿平均分成治疗组和对照组，均对两组患儿实施常规治疗，在常规治疗的基础上予以对照组患儿胞二磷胆碱治疗，予以治疗组患儿神经节苷脂治疗。结果：治疗组患儿的临床治疗总有效率为92.3%，与对照组患儿的74.4%比较差异明显(Plt;0.05)，治疗前两组患儿的NBNA评分(新生儿行为神经测定评分)、CDCC评分(中国儿童发育量表)比较均无明显差异(Pgt;0.05)，治疗后2周、4周治疗组患儿的NBNA评分均高于对照组患儿(Plt;0.05)，出生2个月、3个月治疗组患儿的CDCC评分明显高于对照组患儿(Plt;0.05)。结论：在常规治疗的基础上，应用神经节苷脂治疗新生儿缺氧缺血性脑病，可有效改善患儿神经系统功能，提高患儿临床治愈率。 【关键词】 新生儿；缺氧缺血性脑病；神经节苷脂；临床效果 【中图分类号】 R2 【文献标号】 A 【文章编号】 2095-7165(2015)18-05-02 Neonatal hypoxic-ischemic encephalopathy clinical treatment[Abstract] Objective: To investigate the effective treatment of neonatal hypoxic-ischemic encephalopathy. Methods: A total of 78 cases of childrenwith hypoxic-ischemic encephalopathy participated in the study, and 78 cases of children were divided into treatment group and control group, twogroups of children are on the implementation of conventional therapy, patients in the control group to be treated on the basis of conventional childrenciticoline treatment, be treated group of children ganglioside treatment. Results: Clinical treatment of children with therapy group, the total effective ratewas 92.3%, 74.4% compared with the control group of children with significant differences (Plt;0.05), two groups of children of pre-treatment NBNAscore (neonatal behavioral neurological assessment scores), CDCC Rating (Chinese Child Development Inventory) showed no significant difference(Pgt;0.05), after treatment in children 2 weeks, 4 weeks treatment groups NBNA scores were higher in children (Plt;0.05), was born two months , children3 months of treatment group was significantly higher in children CDCC scores (Plt;0.05).Conclusion: On the basis of conventional therapy, the applicationof ganglioside treatment of neonatal hypoxic-ischemic encephalopathy, which can effectively improve the function of the nervous system in children,improve the clinical cure rate in children.[Key words] newborns; h