无症状幽门螺杆菌对儿童生长发育的影响.docVIP

精品论文 参考文献 无症状幽门螺杆菌对儿童生长发育的影响 广西钦州市妇幼保健院 广西钦州 535000 【摘 要】目的：了解广西沿海地区无症状儿童Hp 感染流行特征，探讨其对儿童生长发育的影响。方法：取368 名3-15周岁，无消化系统症状儿童的血液样本，通过ELISA 法检测血清中幽门螺杆菌抗体（Hp-IgG）；检测身高、体重、腹壁皮下脂肪厚度，随访三年，对比阳性组与阴性组的差异。结果：总体阳性率为13.6%，感染率随年龄段增长而增长。学前组男性第二年脂厚度阳性组低于阴性组（Plt;0.05），学龄组男性第一年体重，脂厚度阳性组低于阴性组（Plt;0.05）。青春组女性第一年体重，第二年身高，第三年身高均阳性组低于阴性组（Plt;0.05）。结论：广西沿海地区无症状儿童幽门螺杆菌阳性率相对偏低，在学前期，学龄期主要影响男性的体重，脂厚度；青春期主要影响对女性的身高与体重。 【关键词】幽门螺杆菌；生长发育；ELISA；广西沿海儿童 The impact of the infection of Helicobacter pylori on the growth and development of children with no symptomsAbstract：objective：This paper investigates the infection of Helicobacter pylori on children with no symptoms and discusses the effectof Helicobacter pylori infection on the growth and development of children in the Northern Gulf of Guangxi.Method：The researchercollects 368 blood samples from 3-15-year-old children with no symptoms of digestive system，and detects the Helicobacter pylori antibody(Hp-IgG) in serum by ELISA；And then the researcher detects the height，weight and abdominal subcutaneous fat thickness of the thesechildren，which are followed up for three years and compares the difference between the positive group and the negative group.Result：Theoverall positive rate of Helicobacter pylori is 13.6%.The infection rate of Helicobacter pylori increases with age.The positive group of theabdominal subcutaneous fat thickness of the pre school males in second year is lower than the negative group（Plt;0.05）.The positive groupof the weight and the abdominal subcutaneous fat thickness of the school age males in the first year is lower than the negative group（Plt;0.05）.The positive group of the weight in the first year， and the height in the first two years of youth females is all lower than thenegative group（Plt;0.05）.Conclusion：The positive rate of Helicobacter pylori on children with no symptoms in The Coastal areas ofGuangxi is relatively low that it mainly influences the weight and abdominal subcutaneous fat thickness