猪肺泡表面活性物质治疗晚期早产儿呼吸窘迫综合症疗效观察.docVIP

精品论文 参考文献 猪肺泡表面活性物质治疗晚期早产儿呼吸窘迫综合症疗效观察 (虞城县人民医院儿科 河南虞城 476300) [摘要] 目的 探讨猪肺泡表面活性物质治疗晚期早产儿呼吸窘迫综合症的临床疗效。方法 选取2014年5月-2015年6月期间在我院接受治疗的晚期早产儿呼吸窘迫70例，随机分成2组，每组35例。对照组进行常规治疗，观察组在常规治疗基础上应用猪肺磷脂治疗。比较两组治疗效果。结果 观察组PaO2、SaO2和PH值明显高于对照组，PaCO2明显低于对照组，差异显著(P＜0.05)；对照组吸氧时间、机械通气时间、呼吸困难消失时间以及住院时间明显高于观察组，差异显著(P＜0.05)。结论 猪肺泡表面活性物质治疗晚期早产儿呼吸窘迫综合症疗效显著，能够有效改善患儿肺功能和临床症状，缩短患儿住院时间，促使患儿早日康复，具有较高的临床应用价值。 [关键词] 猪肺泡表面活性物质；早产儿呼吸窘迫综合症；疗效 Porcine alveolar surfactant therapy in late preterm children with respiratory distress syndrome Efficacy Xue Ying (Yucheng County Peoples Hospital of Henan Yucheng 476300) [Abstract] Objective To investigate the porcine pulmonary surfactant late preterm children the clinical efficacy of the treatment of respiratory distress syndrome. Methods May 2014 --2015 during June in our hospital late preterm children treated 70 cases of respiratory distress, were randomly divided into two groups, 35 cases in each group. Control group conventional treatment, observation group poractant treatment based on routine treatment. Treatment effects were compared. Results observation group PaO2, SaO2 and PH value significantly higher, PaCO2 was significantly lower than the control group, the difference was significant (P lt;0.05); the control group oxygen time, mechanical ventilation time, dyspnea disappeared time and length of hospital stay was significantly higher than the observation group, the difference was significant (P lt;0.05). Conclusion swine alveolar surface active substances in patients with advanced respiratory distress syndrome in premature children significant effect, can effectively improve the clinical symptoms and pulmonary function in children, children with shorter hospital stay, prompting a speedy recovery of children with high clinical value. [Key words] porcine pulmonary surfactant; respiratory distress syndrome in premature children; efficacy 呼吸窘迫综合征是新生儿常见疾病，是指新生儿出生不久后出现呼吸衰竭和呼吸困难等症状，主要原因为肺泡表面活性物质的缺乏，导致肺泡萎陷