理性情绪疗法对化疗期胃癌患者心理及TNF-α水平的影响.docVIP

精品论文 参考文献 理性情绪疗法对化疗期胃癌患者心理及TNF-α水平的影响 杨玲 唐新华 梁嵘 刘媛芳 李永强 陈英 [摘 要]目的 探究理性情绪疗法对化疗期胃癌患者心理及TNF-alpha;水平的影响。 方法 将64例化疗期胃癌患者随机分为观察组和对照组各32 例。同时选择体检32例健康人作为健康对照组。对照组给予常规护理，实验组在此基础上增加理性情绪疗法。干预前后采用症状自评量表(SCL-90)评估患者的心理状态，同时取静脉血4 ml 检测TNF-alpha;的水平。结果 化疗期胃癌组SCL-90 各因子评分显著高于健康对照组；实验组干预后SCL-90 各因子评分显著低于对照组；TNF-alpha;水平显著高于对照组(均P lt;0.01)。 结论 理性情绪疗法可改善化疗期胃癌患者心理状态，提高其免疫功能。 [关键词]理性情绪化疗法 胃癌化疗期患者 心理状态 TNF-alpha;水平 DOI:10.3760/cma.j.issn.1674-2907.2016.9.1036 ??金项目：广西壮族自治区卫生厅自筹经费科研课题(Z2012350, Z2015576)；广西高等学校科研课题（201204LX058） 作者单位：530021，广西南宁市，广西医科大学附属肿瘤医院 通讯作者：陈英，广西医科大学附属肿瘤医院消化肿瘤内科 Effect of rational emotive therapy on chemotherapy in patients with gastric cancer and TNF- levels of psychological Yang Ling,Tang Xinhua,Liang Rong,Liu Yuanfang,Li Yongqiang,Chen Ying Abstract: Objective To observe the effect of rational emotive therapy on the psychological state and level of TNF-alpha; of the patients with gastric cancer during chemotherapy. Methods A total of 64 cases, which were separate into two groups, experimental group (32 cases) and control group (32 cases). And we also choose 32 healthy man as healthy control group. Control group was carried into regular care, while experimental group was carried into regular care and rational emotive therapy. Their psychological state were tested by SCL-90 before and after treatment. And we also need to take 4ml venous blood from them to exam their TNF-alpha; level. Results After nursing intervention， SCL- 90 scores in the observation group were lower than that in the control group，SCL-90 scores of the experimental group--patients with gastric cancer during chemotherapy-- are higher than the healthy control group. After experiment, SCL-90 scores of the experimental group are lower than the control group, while the level of TNF-alpha; are higher than the control group. Conclusion Rational emotion therapy has positive significance to adjust psychological state, improve their immune function of the patients with gastric cancer during ch