益气涤肠通腑汤对COPD患者部分脱机指标的影响.docVIP

精品论文 参考文献 益气涤肠通腑汤对COPD患者部分脱机指标的影响 金晓烨1 杨超1 赵新爱2 贺丽1 （1开封市第二人民医院ICU 河南开封 475002；2开封市第二人民医院中医科 河南开封 475002） 【中图分类号】R249 【文献标识码】B 【文章编号】1672-5085（2010）34-0425-03 【摘要】目的 观察益气涤肠通腑汤对COPD病人脱机指标的影响。方法 125例腹胀的COPD患者随机分为实验组（益气涤肠通腑汤治疗组n=65）及对照组（n=60），两组均使用抗生素、解痉、化痰、益生菌等治疗，实验组加用益气涤肠通腑汤治疗。呼吸机采用SIMV+PSV模式，观察15天。结果 实验组治疗6天后自主潮气量、最大吸气负压明显增加，腹胀症状明显改善，P0.1和RSBI均明显改善，和对照组相比均有统计学意义，实验组脱机成功率有增高趋势，但与对照组相比无统计学意义（38.5% VS 20％，Pgt;0.05）；12天时实验组P0.1和RSBI均进一步改善，和对照组相比均有统计学意义，脱机成功率明显高于对照组（80% VS 41.7％，Plt;0.01）；应用益气涤肠通腑汤前后血生化指标稳定。结论 益气涤肠通腑汤对腹胀的COPD病人，能有效改善腹胀等症状，改善脱机指标，提高脱机成功率。 【关键词】机械通气 脱机 益气涤肠通腑汤 慢性阻塞性肺病（COPD） The influence of part predictors for weaning on treatment with Yiqi Dichang Tongfu decoction for weaning patients with COPD JIN Xiaoye, YANG Chao,ZHAO Xinai, he li 【Abstract】 Objective: To observe the influence of predictors for weaning on treatment with Yiqi Dichang Tongfu decoction for weaning patients with COPD. Methods: 125 cases weaning patients with COPD were randomized into two groups: the treatment group(n =65)based on conventional therapy of western medicine added Yiqi Dichang Tongfu decoction and the control group(n =25)based on conventional therapy of western medicine. All patients had been treated for 15 days. Results: The sTv , MIP were increased obviously and the clinical symptoms were improved by various degrees, P0.1and RSBI were significantly improved in the treatment group compared with the control group after six days treatment. The successful rate of weaning in the treatment group was significantly higher than that in control group( 80% VS 44%, Plt;0.01) after useing decoction for 12 days. All biochemical markers are stable before and after the treatment. Conclusions: For weaning patients with COPD the Yiqi Dichang Tongfu decoction is able to improve the digestion functions, to increase the pneumodynam, to improve the predictors of weaning and to increase the successful rate of weaning. 【Key word】 mechanical ventilation weaning Yiqi Dichang