盐酸氮卓斯汀滴眼液联合普拉洛芬滴眼液治疗儿童过敏性结膜炎的临床效果.docVIP

精品论文 参考文献 盐酸氮卓斯汀滴眼液联合普拉洛芬滴眼液治疗儿童过敏性结膜炎的临床效果 南华大学附属第二医院眼科 湖南衡阳 421001 【摘 要】目的：探讨盐酸氮卓斯汀滴眼液联合普拉洛芬滴眼液治疗儿童过敏性结膜炎的临床效果。方法：选取66例儿童过敏性结膜炎患者，随机分为研究组和对照组，每组33例。对照组行盐酸氮卓斯汀滴眼液治疗，研究组在对照组的基础上加行普拉洛芬滴眼液治疗，于治疗后7 d分别观察2组患者症状体征的改善情况和总体疗效，并进行比较。结果：（1）.治疗7d后，2组患者症状体征评分均较治疗前有所改善，且研究组优于对照组（Plt;0.05）；（2）.研究组7 d总有效率为81.8%，高于对照组54.5%，差异有统计学意义（Plt;0.05）。结论：盐酸氮卓斯汀滴眼液联合普拉洛芬滴眼液治疗儿童过敏性结膜炎在患者临床症状与体征改善方面效果明显，临床疗效明显优于单用盐酸氮卓斯汀滴眼液等常规抗过敏药物疗效，值得推广应用。 【关键词】儿童；过敏性结膜炎；盐酸氮卓斯汀；普拉洛芬 Abstract：Objective：To investigate the clinical effects of Azelastine Hydrochloride Eye Drops and Pranoprofen Eye Drops in treatment of children allergic conjunctivitis. Methods：66 children with allergic conjunctivitis were randomly divided into study group and control group，with 33 cases in each group. The control group was treated with hydrochloric acid nitrogen Zhuo sting eye drops treatment，study group on the basis of the control group preliminaries of pranoprofen eyedrops treatment，after treatment of 7 days were observed 2 groups in patients with symptoms and signs of improvement and overall efficacy and compared. Results：（1）After 7d treatment，2 groups of patients with symptoms and signs were improved compared with before treatment，and the study group than the control group（Plt;0.05）；（2）The total effective rate of the study group was 7，54.5% higher than that of the control group（81.8%），and the difference was statistically significant（Plt;0.05）. Conclusion：Azelastine hydrochloride drops of eye drops combined with pranoprofen eye drops in the treatment of children allergic conjunctivitis in patients with clinical symptoms and signs improved obvious effect，clinical curative effect is obviously superior to the single use Azelastine hydrochloride drops of eye drops and so on conventional anti allergy drug efficacy，worthy of popularization and application. Key words：Children；Allergic conjunctivitis；Azelastine；Pranoprofen 0引言 过敏性结膜炎是一种临床上十分常见的眼表过敏性疾病，发病率非常高，约为20% [1]，儿童群体尤其高发。随着现代化社会的发展，空气污染指数不断升高，其发病率逐年上升