翼状胬肉两种不同切除术患者泪液功能的临床分析.docVIP

精品论文 参考文献 翼状胬肉两种不同切除术患者泪液功能的临床分析 李大鹏（通讯作者） 戴静 （江苏省东海县人民医院眼科 222300） 【摘要】目的 探讨两种不同手术方式治疗翼状胬肉对泪液功能的影响及影响因素。方法 选取翼状胬肉患者60例（60只眼）随机分成两组：A组30个病人（30只眼）翼状胬肉联合结膜瓣移植术；B组30个病人（30只眼）翼状胬肉切除联合带自体角膜缘干细胞结膜瓣移植术。术前，术后4周，术后12周行泪膜破裂时间（BUT）、泪液分泌试验（Schirmer I）、角膜荧光素染色（CSF）,评价翼状胬肉及翼状胬肉切除术后泪膜功能变化对患者生活质量的影响。结果 两组病人术后4周BUT缩短，角膜荧光素染色增多，差异有统计学意义(plt;0.05),而术后Schirmer I与术前相比无统计学意义，两组术后12周BUT, Schirmer I, CFS与术前相比无统计学意义，翼状胬肉切除联合带自体角膜缘干细胞结膜瓣移植术组术后早期泪膜稳定性优于翼状胬肉联合结膜瓣移植术，差异具有统计学意义(plt;0.05).结论 翼状胬肉切除术早期对泪膜功能有影响。翼状胬肉切除联合带自体角膜缘干细胞结膜瓣移植术早期对泪膜的影响小于翼状胬肉联合结膜瓣移植术。 【关键词】翼状胬肉 泪膜 翼状胬肉切除 角膜缘干细胞 【中图分类号】R777.33 【文献标识码】A 【文章编号】2095-1752（2013）27-0072-02 Clinical analysis of two different surgical methods on tear function in patients with pterygium LI Da-peng,Daijing,Departmeng Of Ophthalmology,the Peoplersquo;Hospital of Donghai County,Donghai County 222300,China Corresponding author:li dapeng, Email163.com 【Abstract】Objective To explore the two different surgical methods on tear function in patients with ptergium and its possible factors.Method Sixty cases of pterygium patients (60 eyes) were randomly divided into two groups: A group of 30 patients (30 eyes) underwent pterygium excision combined with conjunctival flap,B group of 30 patients (30 eyes) underwent wing-shaped pterygium excision combined with autologous limbalstem cell transplantation . Respectively before and 4 weeks ,12weeks after surgery the tear film break-up time (BUT), Schirmer I test, conjunctiva fluoresce in staining (CFS)，To evaluate the effects of tear function changes in pteryqium and on quality of patients life after pterygium excision 。Results Of two groups of patients 4weeks post-operation BUT shortened, CFS increased, and the differences were significant (plt;0.05), while the difference between postoperative and preoperative Schirmer I was insignificant, As for 12 weeks post-operation BUT, Schirmer I, CFS postoperative and preoperative difference of two groups