老年糖尿病人凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）水平改变的临床研究.docVIP

精品论文 参考文献 老年糖尿病人凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）水平改变的临床研究 王芳1 王德忠2 杨乃龙1 　　（1青岛大学附属医院 山东青岛 266000） 　　（2山东省滕州市中心人民医院 山东滕州 277500） 　　【摘要】目的：观察老年糖尿病人凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）水平等指标改变。方法：选择住院的老年糖尿病患者98例，对98例老年糖尿病患者（男、女各49例）分成无慢性血管性并发症组（A组）、有慢性血管性并发症组（B组），同时设对照组。分别观测血中凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）水平等指标的改变。结果：与对照组相比，老年糖尿病患者的血浆PT、APTT水平明显降低（Plt;0.01）,且有慢性血管性并发症者降低更为显著（Plt;0.01）；FIB的水平均明显升高（Plt;0.01），且有慢性血管性并发症者升高更为显著（Plt;0.01）。结论：老年糖尿病患者存在血浆PT、APTT、FIB水平明显的异常，且以有慢性血管病变者更为显著。 　　【关键词】老年糖尿病；凝血酶原时间（PT）；活化部分凝血活酶时间（APTT）；纤维蛋白原（FIB） 　　【中图分类号】R587.1 【文献标识码】A 【文章编号】1007-8231（2015）16-0024-02 　　Clinical study on changes of Expression of Prothrombin Time (PT) , Activated Partial Thromboplastin Time (APTT) and Fibrinogen (FIB) in Patients with senile Diabetes. Wang Fang,Wang Dezhong,Yang Nailong . 　　1.The Affiliated Hospital of Qing Dao Vniversity.2.Tengzhou Central Pepolersquo;s Hospital of ShanDong Province,China 　　【Abstract】Objective To observe the clinical significance of the changes of prothrombin time (PT) , activated partial thromboplastin time (APTT) and fibrinogen (FIB)in patients with senile diabetes mellitus.Methods 98 hospitalized cases (male and female,49,each) with senile diabetes mellitus were selected, and they were divided into two groups (Group A, without chronic vascular complications and Group B, with chronic vascular complications). Control Group was also designed. The changes of prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) in blood were determined.Results Compared with those of Control Group, the levels of PT and APTT in plasma were all decreased obviously in patients with senile diabetes mellitus(Plt;0.01), and the results of Group B were lower than those of Group A. The level of fibrinogen (FIB) was increased compared with those of Control Group (Plt;0.01). The increase of Group B was higher obviously than those of Group A (Plt;0.01).Conclusion T