瑞舒伐他汀联合普罗布考抗动脉粥样硬化的临床观察.docVIP

瑞舒伐他汀联合普罗布考抗动脉粥样硬化的临床观察 　　[摘要]目的 ?^察瑞舒伐他汀联合普罗布考治疗动脉粥样硬化的效果。方法 收集2013年1月～2015年6月在我院治疗的冠180例心病患者作为研究对象。随机分为联合组、瑞舒伐他汀组和普罗布考组，各组均60例，治疗6个月。联合组给予瑞舒伐他汀联合普罗布考片治疗，瑞舒伐他汀组只给予瑞舒伐他汀口服，普罗布考组只给予普罗布考治疗。统计各组的治疗有效率，检测血清胆固醇、高密度脂蛋白及低密度脂蛋白水平，计算颈动脉内中膜厚度，评估三组的治疗效果。结果 联合组的总有效率显著高于瑞舒伐他汀组和普罗布考组，差异有统计学意义（P0.05）。联合组治疗前后的血总胆固醇、血高密度脂蛋白、低密度脂蛋白、颈动脉内中膜厚度比较，差异有统计学意义（P 　　[关键词]瑞舒伐他汀；普罗布考；冠心病；临床效果 　　[中图分类号] R543 [文献标识码] A [文章编号] 1674-4721（2017）04（a）-0048-05 　　Clinical observation of Rosuvastatin combined with Probucol in the treatment of atherosclerosis 　　ZOU Yan-ming1 YAO Yuan-ying2 LI Rong3 XIN Hui4 　　1.Department of Internal Medicine-Cardiovascular，Weihaiwei People′s Hospital of Weihai City in Shandong Province，Weihai 264200，China；2.Department of Pediatrics，Maternal and Child Health Care Hospital of Huancui District of Weihai City in Shandong Province，Weihai 264200，China；3.Electrocardiographic Room，Medical College of Qingdao University，Qingdao 266000，China；4.Department of Internal Medicine-Cardiovascular，Affiliated Hospital of Medical College of Qingdao University，Qingdao 266000，China 　　[Abstract]Objective To obsreve the effect of Rosuvastatin combined with Probucol in the treatment of atherosclerosis.Methods 180 cases of coronary heart disease from January 2013 to June 2015 treated in our hospital were selected and randomly divided into the combination group，the Rosuvastatin group and the Probucola group，60 cases in each group.All of them were treated for 6 months.The combined group was treated with Rosuvastatin combined with Probucol Tablets，the Rosuvastatin group was only given Rosuvastatin，the Probucol group was only given Probucol.The effective rate of each group was measured，the levels of serum cholesterol，high density lipoprotein and low density lipoprotein were detected，and the intima-media thickness of carotid artery was calculated.The therapeutic effects of the three groups were evaluated.Results The total effective rate of the combined group was significantly higher than that of t