贝那普利联合阿托伐他汀在2型糖尿病并发肾病患者治疗中的临床价值.docVIP

精品论文 参考文献 贝那普利联合阿托伐他汀在2型糖尿病并发肾病患者治疗中的临床价值 （重庆市綦江区人民医院消化内分泌科 重庆 401420） 【摘要】 目的：探讨贝那普利联合阿托伐他汀在2型糖尿病并发肾病患者中的疗效。方法：将2型糖尿病并发肾病患者82例随机分为两组，均行糖尿病常规治疗，对照组41例采用贝那普利治疗，观察组41例采用贝那普利联合阿托伐他汀治疗，比较两组治疗前后临床指标、治疗效果。结果：治疗后，两组TC、TG、UAER、Scr、BUN、MALB、beta;2MG、FPG均显著降低（P＜0.05）。观察组TC、TG、UAER、Scr、BUN、MALB、beta;2MG均明显低于对照组（P＜0.05），治疗总有效率明显高于对照组（P＜0.05）。结论：贝那普利联合阿托伐他汀治疗2型糖尿病并发肾病的效果显著。 【关键词】 贝那普利；阿托伐他汀；2型糖尿病；肾病 【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752（2016）02-0211-02 Clinical value of benner pury combined with atorvastatin in treatment of patients with type 2 diabetic nephropathy Tan Xiaomei Qijiang District Peoples Hospital of Chongqing District 【Abstract】Objective To investigate effect of benner pury combined with atorvastatin in treatment of patients with type 2 diabetic nephropathy. Methods 82 patients with type 2 diabetic nephropathy were randomly divided into two groups, who received conventional treatment of diabetes.41 patients treated benner pury as control group. 41 patients treated benner pury combined with atorvastatin as observation group. Clinical indicators before and after treatment, treatment effect were compared between two groups. Results After treatment, TC, TG,, UAER, Scr, BUN, MALB,beta;2MG,,FPG significantly decreased in two groups (Plt;0.05). TC, TG, UAER, Scr, BUN, MALB,beta;2MG in observation group were significantly lower than control group (Plt;0.05). Total effective rate in observation group was significantly higher than control group(Plt;0.05). Conclusion Benner pury combined with atorvastatin has significant effect in treatment of patients with type 2 diabetic nephropathy.. 【Key words】Benner pury; Atorvastatin; Type 2 diabetes; Nephropathy 2型糖尿病患者并发肾病的风险性较高[1]，是一种常见的全身性微血管并发症，虽然不会加速糖尿病病程，但会引起肾衰竭而危及患者生命。近年来，糖尿病肾病的发病率持续走高[2]，越来越受到人们关注。对其治疗，目前临床以药物治疗较为常用。此次研究将2型糖尿病并发肾病患者82例随机分为两组，实施不同的治疗方案进行对比分析，现报道如下。 1.资料与方法 1.1 资料 本院2012年10月～2014年10月诊治的2型糖尿病并发肾病患者82例，均符合《内科学》的诊断标准[3]，排除患有器质性疾病、血液性疾病、感染性疾病、