静脉血栓栓塞症危险因素2012-5-26PPT.ppt

静脉血栓栓塞症的危险因素;VTE = PTE + DVT; 高发病率 高病死率 “多发而少见” —— 根源：高漏诊率 + 高误诊率;流行病学资料;流行病学情况;警惕 VTE的发生;PREVENTION IS KEY!!;Virchow’s 三要素;Virchow’s 三要素;;The incidence of DVT correlates with the total number of risk factors;临床危险因素识别;遗传性易栓症;高加索人群遗传性易栓症的发病率;DVT患者中FV Leiden突变;DVT患者中凝血酶原基因G20210A突变; DVT患者中抗凝蛋白缺乏;抗凝蛋白 缺乏;何时怀疑遗传性易栓症;遗传性易栓症与VTE复发相关;易栓症患者VTE的预防;环境和人群相关危险因素;Incidence of VTE by sex and age;British Journal of HaematologyVolume 139, Issue 2, pages 289-296, 25 SEP 2007 DOI: 10.1111/j.1365-2141.2007.06780.x/doi/10.1111/j.1365-2141.2007.06780.x/full#f1;The risk of venous thrombosis: obesity and travel;预防-ACCP9版指南;外科手术或创伤相关危险因素;???院患者发生DVT的风险;骨科大手术后VTE发生率较高;;每个国家地区入组的病例数;DVT发病率;总 DVT (%) ;60.0;骨科大手术患者VTE的危险分度;预防-ACCP 9版指南;内科疾病相关危险因素;肿瘤与VTE;;预防-ACCP 9版指南;;医源性干预措施相关因素;VTE风险评估;Well’s Criteria (DVT);Well’s Criteria（PE）;Revised Geneva score;Caprini Risk Assessment Model;Caprini Risk Assessment Model;;E-Alerts Can Increase Prophylaxis;;Intervention;Effectiveness can wane over time;*