抗生素PPT课件（英文精品） Penicillin-resistant pneumococci potentials for modeling(57p)PPT.ppt

Penicillin-resistant pneumococci - potentials for modeling;About the bug;Surface capsular polysaccharide;Polysaccharide capsule;Pathogenesis;Important for modelling:Pneumococcal serotypes; ;Important for modelling:Pneumococcal serotypes (II);Pneumococcal vaccine Antibody response in young children;Important for modelling:Capsular switch;About the disease;Meningitis Pneumonia Pericarditis Septicemia Osteomyelitis;Significant disease burden in children;Etiology of acute otitis media(South Sweden);Acute otitis media;;;Invasive pneumococcal disease (IPD);Main clinical picture IPD(South Sweden);;;Age-related incidence of IPD (Europe 2005);Incidence of invasive pneumococcal disease in children (US 1998);Seasonality IPD (Europe 2005);Important for modelling:Pneumococcal carriage;?ldersrelaterad b?rartid;B?rartid av pc-resistenta pneumokocker;Important for modelling:Role of day care centres (DCC);Black S, Shinefield H. Pediatr Ann. 1997;26:355-360.;Antibiotic resistance; Streptococcus pneumoniae: patterns of penicillin non-susceptibility;Sales of antibiotics in the EU;Penicillin-resistant pneumococci;Antibiotic usage for acute otitis media by age (US);Penicillin-resistant pneumococci (I+R);Important for modelling:Risk factors for resistance;Child serotypes and resistance;Risk factors for PRP-carriagein day-care centres;Penicillin-binding proteins and?-lactam resistance;Important for modelling:PRP development (Baquero);PRP utveckling (Baquero);PRP utveckling (Baquero);PRP utveckling (Baquero);;1. Malm? (0195) 8. K?vlinge (06-95) 2. Staffanstorp (03-95) 9. Trelleborg (08-95) 3. Vellinge (03-95) 10. Helsingborg (08-95) 4. Landskrona (04-95) 11. Burl?v (09-95) 5. H?gan?s (04-95) 12. Lomma (10-95) 6. Lund (04-95) 13. H??r (12-95) 7. Esl?v (04-95) 14. Sval?v (01-96) 15. Svedala (02-96) 16. Skurup (03-96) 17. Bjuv (--) 18. H?rby (--) 19. Sj?bo (--) 20. Ystad (--);PRP and antibiotic consumption in children;Basic reproductive rate