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JOURNAL OF MAGNETIC RESONANCE IMAGING 24:248–255 (2006)
Technical Note
Discrepancy-Based Adaptive Regularization for
GRAPPA Reconstruction
Peng Qu, PhD, Chunsheng Wang, PhD, and Gary X. Shen, PhD*
sensitivity encoding (SENSE) (2) have proven practical
Purpose: To develop a novel regularization method for
in a wide range of applications to accelerate MRI scan-
GRAPPA by which the regularization parameters can be
optimally and adaptively chosen. ning. By using sensitivity information from an RF coil
array to perform some of the spatial encoding, parallel
Materials and Methods: In the fit procedures in GRAPPA, imaging techniques allow a reduction in the phase-
the discrepancy principle, which chooses the regularization
encoding steps and thus decrease the scan time.
parameter based on a priori information about the noise
level in the autocalibrating signals (ACS), is used with the Generalized autocalibrating partially parallel acquisi-
truncated singular value decomposition (TSVD) regulariza- tion (GRAPPA) (3) is currently a leading k-space-based
tion and the Tikhonov regularization, and its performance parallel imaging technique. GRAPPA essentially com-
is compared with the singular value (SV) threshold method bines several advantages of previous improvements to
and the L-curve method, respectively by axial and sagittal SMASH (4–8), including autocalibration, coil-by-coil
head imaging experiments.
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