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ANNUAL Further Fat and Beyond: The
REVIEWS
Click here for quick links to
Annual Reviews content online, Diverse Biology of PPARγ
including:
• Other articles in this volume
• Top cited articles Peter Tontonoz1 and Bruce M. Spiegelman2
• Top downloaded articles
• Our comprehensive search 1
Howard Hughes Medical Institute and Department of Pathology and Laboratory
Medicine, University of California, Los Angeles, California 90095;
email: ptontonoz@
2 Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical
School, Boston, Massachusetts 02115; email: bruce spiegelman@
Annu. Rev. Biochem. 2008. 77:289–312 Key Words
First published online as a Review in Advance on adipocyte, inflammation, insulin sensitivity, metabolism,
March 20, 2008
macrophage, nuclear receptor, thiazolidindione
The Annual Review of Biochemistry is online at
Abstract
This article’s doi: The nuclear receptor PPARγ is a ligand-activated transcription fac-
10.1146/annurev.biochem.77.061307.091829 tor that plays an important role in the control of gene expression
c
Copyright 2008 by Annual Reviews. linked to a variety of physiological processes. PPARγ was initially
All rights reserved
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