黑茶营养干预代谢综合征生理功效的研究现状及发展趋势.docVIP

黑茶营养干预代谢综合征生理功效的研 究现状及发展趋势 蒙述霖呈星豪朱继荷黎勇郑志兵覃思 湖南农业大学食品科学技术学院 黑茶是屮国一大特有的发酵茶类，近年来因被报道具有降低血脂、改善血压、调 节血糖等功效而备受关注。然而，相比于绿茶和红茶，FI前尚无系统性地有关黑 茶改善代谢综合征功效及其分子机理研宄现状的综述。通过全面总结和分析，迄 今为止国内外学者在细胞、动物和人体临床水平上关于黑茶改善糖脂代谢异常现 象的研宄数据，发现黑茶确实能在一定程度上降低体重并改善糖脂代谢综合征， 但其分子机制研究相对较少，人体临床数据累积不足，丑黑茶的安全毒理性评 价亦缺乏。所以，黑茶有效成分的结构鉴定及其在不同细胞系中的分子机理亟待 系统性研宄，动物实验需耍更为科学合理的设计，人体临床数据有待进一步的 积累，这样才能更安全有效地发挥干预代谢综合征的功效，加速其在保健食品 或药品领域的应用。 关键词： 黒茶;代谢综合征;功效?，营养干预; 蒙沛霖（1995一），女，本科生，研究方向：营养与食品卫生。 覃思（1981—），男，，副教授，研究方向：食品分子功能及营 养基因组学。 基金：国家自然科学某金项FI （项目编号 Research Status and Development Trend of Nutritional Intervention Function of Dark Tea on Metabolic Syndrome MENG Pei-lin LV Cheng-hao ZHU Ji-he LI Yong ZHENG Zhi-bing QIN Si College of Food Science and Technology， Hunan Agricultural University; Abstract： Dark tea, as a special kind of fermented tea in China, is recently concerned owing to its biological function of regulation in blood lipid, blood pressure and blood glucose. Nevertheless, there is no systematic review about the efficiency of dark tea on improving metabolic syndrome (Mets) and its underlying molecular mechanisms, comparing with green tea and black tea. By comprehensively summarizing and analysing the present research data on the improvement of Mets in cells, animals and human body by dark tea intake or treatment, the results revealed that dark tea could reduce the body weight and improve the Mets in a certain degree. However, there is limited study on the molecular mechanism of this function, lack of clinic trial on its efficiency and most importantly, there is inadequate data on the safety and toxicity evaluation of dark tea in the body. Consequently， the structures of its active ingredients and the molecular mechanisms in diverse cell types need to be well systematically investigated, animal experiments need to be better scientifically designed, and the human clinical data require to be more accumulated. Only in this way will it intervene with metabolic syndrome more safely and more efficient