夭津医科大学学报.pdfVIP

夭津医科大学学报 V.1， 236 1TMU 2001 N..2 干扰素7对烧伤增生性瘫痕色度值变化的影响* 张明谏 ，‘王其芳’.宁恩弟’，张静琦肚，万柏冲2，曲 听2 (1天津市第一中心医院烧伤整形科 300192;2天津大学精密仪器与光电子工程学院) [摘 要1目肠:观察干扰素Y治疗烧伤增生性w痕后0痕色度值的变化 方孩:选择烧伤后服痕患者38例 疲痕内 注射重组干扰素Yloo万国际单位，每周一次，连续江射4次。选同体夜痕用注射灭菌注射用水治疗作对照，于治疗 前和治疗后4周和8周，用光电检测技术测量瘫痕的色度值，并观察患者的自觉症状(痒、胀、痛)A痕的充血、颜色 等变化。抽果:用干扰素Y治疗增生性振痕后4周、8周，振痕的色调、饱和度值均明显低于对照组(P0.01),患者 的白觉症状(痒、胀、痛)减轻、振痕的充血减轻、颜色变浅。蛤铬:用千扰素了治疗增生性疲痕后盛痕的色度值明显 降低，干扰素Y是治疗增生性疾痕疗效明显的药物之一。 1关键词1千扰索Y;瘫痕;色度分析 f中困分类号1R644 f文献标识码1A 文【章编号11006一8147(2001)02一0236一03 Effectsofinterferon一yonchangesofchromavaluesinburned hypertrophicscartissue ZHANGMing一jian，‘WANGQi一fang,NingEn一di’ZHANGling一9t’，WANBai一kun,QUXin (1.DepartmentofRumsandPlasticSurgery,Tia哟mFirstCentralHospital,300192;2.CollegeofPrecision InstrumentandOpto一electronicEngineering,TianjinUniversity) ABSTRACTObjective:Toobservechangesofchromavalueinburnedhypertrophicscartissue afterusinginterferon一ytreatment.Methods:Chromavaluesofhypertrophicscarswerede- terminedbyphoto一electricitytesttechnology,changesofhyperaemiaofscartissueandscar colouraswellasotherphysiologicalsymptomsin38burnedpatientswereobservedbeforeusing interferon一ytreatment,andduringweeks4and8afterusinginterferon一ytreatmentoncea week(total4weeks).Thecontrolgroupreceivedsterilewaterinjectionstothescartissue.Re- suits:Thevaluesofhueandsaturationofhypertrophicscarsfromweeks4and8afterusing interferon一ytreatmentwerelowerthanthoseinthecontrolgroup(P0.01).Physiological symptomsinpatientswererelieved,hyperaemiaofseartissueandscarcolourallimprovedsig- nificantly.Conc