抗生素英文课件精品 Antimicrobial Drugs(24p).pptVIP

Antimicrobial Drugs;Antimicrobial Drugs;Historical Perspective;1928 – Fleming discovered penicillin, produced by Penicillium. 1940 – Howard Florey and Ernst Chain performed first clinical trials of penicillin.;Properties of an ideal antibiotic;Major genera that produce clinically useful antibiotics ;Major targets of antimicrobial activity;Major targets of antimicrobial activity;Penicillin Natural penicillins Semisynthetic penicillins Penicilinase-resistant penicillins Extended-spectrum penicillins Penicillins + ?-lactamase inhibitors Carbapenems Monobactam ;Antibacterial Antibiotics Inhibito