基础医学 呼吸系统疾病幻灯片课件.ppt

department of pathology alveolus Lobar pneumonia Lobular pneumonia Bacterial pneumonia Legionella pneumonia interstitium(bronchiole) department of pathology department of pathology department of pathology Primary cancer of the lung Most common primary malignant tumour Directly related to cigarette smoking Associated with occupational exposure to carcinogens Overall 5-year survival rate of 4-7% Squamous cell, small cell, adenocarcinoma, and large cell undifferentiated types department of pathology morphology department of pathology This is a squamous cell carcinoma of the lung that is arising centrally in the lung . department of pathology department of pathology This tumor arise near the hilus of the lung . department of pathology department of pathology department of pathology Diffuse type lung carcinoma Metastasic carcinoma department of pathology This is a peripheral adenocarcinoma of the lung. Adenocarcinomas and large cell anaplastic carcinomas tend to occur more peripherally in lung. The solitary appearance of this neoplasm suggests that the tumor is primary rather than metastatic. department of pathology Histological classification Nor small cell lung carcinoma(NSCLC) Squamous cell carcinoma(50-60%) adenocarcinoma(13-15%) Large cell carcinoma(15-20%) Small cell lung carcinoma(SCLC) “oat cell carcinoma”(10-20%) department of pathology Squamous cell carcinoma of lung department of pathology department of pathology Oat cell carcinoma of lung department of pathology Spread and metastasis Direct spreading Lymphatic metastasis Hematogenous metastasis department of pathology This is sqamous cell carcinoma that extends from hilum to pleura. department of pathology department of pathology Lymphatic metastasis department of pathology department of pathology department of pathology department of pathology department of pathology department of pathology department of pathology Nasopharyngeal carcinoma Chronic bronchitis Chronic constructive emphyse