Respiratory Pharmacology - Coast Colleges Home Page呼吸药理学-海岸学院主页.pptVIP

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Respiratory Pharmacology - Coast Colleges Home Page呼吸药理学-海岸学院主页.ppt

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Respiratory Pharmacology RC 195 Dan Farrell Goal of Respiratory Care:Airway Maintenance Two ways to name a drug: Brand (Trade) name and Generic Name Respiratory Pharmacology Calculations Definitions Solute – material to be dissolved Usually the actual drug Solvent – the dissolving or diluting medium Almost always is water! Handy Conversions 1 ml = 1 cc 1 gm = 1000mg 1 gm H2O = 1 ml H2O 1 lbs = 454 gms 1 kg = 2.2 lbs 3 Ways to Express Drug Strength “X” mg/ml Tells how many milligrams of drug (solute) are in each ml of solution (solvent) 10 mg/ml = 10 milligrams of drug in each ml of solution Best form to use for most calculations! % Solution “X” grams of solute (drug) in each 100 ml of solvent (solution) 1% solution = 1 gram of solute (drug) in each 100 ml of solvent (solution) Is also the same strength as 10 mg/ml since 1% = 1gm/100ml = 1000mg/100 ml = 10 mg/ml Dilution Ratio 1 gram solute (drug) per “X” grams (or ml) of solvent (solution) 1:100 = 1 grams of drug (solute) per 100 grams of solvent (or ml of solution) 1:100 = 1000mg/100 ml = 10 mg/ml 10 mg/ml, 1% and 1:100 are all the same strength just expressed 3 different ways Conversions: mg/ml to % solution Move decimal point 1 place to the left! 10 mg/ml = 1% 75 mg/ml = 7.5% Conversions: % solution to mg/ml Move decimal point 1 place to the right! 2% = 20 mg/ml .5% = 5mg/ml 7.5% = 75 mg/ml Conversions: Dilution Ratio to % Solution Convert to mg/ml and then move decimal point 1 place to the left! 1: 1000 = 1 gram per 1000 grams = 1000mg/1000 ml (why?) = 1 mg/ml = .1 % Conversions: mg/ml or % solution to a dilution ratio If in mg/ml, first change to % solution, then express the % solution by its definition and then divide it out Crystal clear, isn’t it!?!?!? 20 mg/ml = 2% solution By definition, a 2% solution is 2 grams of solute (drug) in every 100 grams of solvent (solution) or 2: 100 By dividing it out, you get the true dilution ratio: 2:1