aids与非aids患者肺毛霉菌病影像表现对比研究分析 word格式.docxVIP

结论肺毛霉菌病的影像表现可多种多样；肺毛霉菌病在非 AIDS 组以肺部渗出性改 变明显；在 AIDS 组则以双肺多发粟粒样结节影为特点。关键词：获得性免疫缺陷综合征；肺；毛霉菌病；放射学；体层摄影；X 线计算 机Analysis andComparison of Radiographic Characteristics of Pulmonary Mucormycosis in Patients withand without AIDSName:Huiming LiMentor:Professor WU XiaomeiAbstractObjectiveTo study the radiographic characteristics of pulmonary mucormycosis in patients with and without acquired immunodeficiency syndrome (AIDS).Material and methods33 patients diagnosed pulmonary mucormycosis by fungal culture were retrospectively studied . Their chest X-ray or/and CT scan data were analysed. The patients were categorized into two groups for further studied : AIDS group (n=24) and non-AIDS group (n=9 ). The imaging menifestations were observed, which including distribution , quantity, shape, size, density and boundary of nidus in lung, lymph nodes, interstitial changes.ResultsThe general imaging appearance found in both two groups are including increased bronchovascular shadows, airspace consolidation, pulmonary nodules, ground-glass attenuation, pneumatocele, enlarged hilar and mediastinal lymph nodes, pleural effusion et al. . Airspace consolidation were significantly more common in nonAIDS group than in AIDS group (p =0.032 ). Pulmonary nodules were significantly less common in AIDS group than in AIDS group (p =0.039 ).ConclusionsThe imaging appearances of pulmonary mucormycosis were various. The inflammatory response were more obvious.in pulmonary mucormycosis of patients without AIDS the pulmonary nodules were the characteristics of pulmonary mucormycosis in patients with AIDS .Keywords:Acquired Immunodeficiency Syndrome; Lung; Mucormycosis; Radiography; Tomography, X-Ray Computed前言2009 年，中国卫生部、联合国艾滋病规划署(UNAIDS)以及世界卫生组织(WHO)对中国艾滋病疫情做了估计，截至 2009 年底，中国现存活艾滋病病毒感染 者和艾滋病患者(HIV/AIDS)大约 74 万(56 万—92 万)，全人群感染率为 0．057％ (0．042％—0．071％)；其中艾滋病患者 10．5 万(9．7 万—11．2 万)。艾滋病是由人类免疫缺陷病毒（HIV)感染后引起的人体免疫缺陷临床综合征， 也称为获得性免疫缺陷综合征（AIDS）。HIV 进入人体后可持续破坏机体免疫功能， 最后造成机体免疫功能缺陷，患者免疫力受损，容易并发机会性感染（OIs