基于fmri的神经活动研究-生物医学工程专业论文 word格式.docxVIP

ABSTRACTABSTRACTFor a long time exploring human brain has been a goal for the humanbeings to pursuit. The rapid development of medical imaging technology, especially functional imaging technology makes the humanbeings increasingly close to this goal. Magnetic resonance imaging is a non-invasive technique to accurately study the human brain and is also important for medical diagnosis. With the basic research processing in human brain functional magnetic resonance imaging, the application of fMRI in cognitive neuroscience research has gradually increased. In our study, fMRI was mainly used to investigate the neural mechanism of decision-making under risk.The brain regions activated by sequential finger movements of different complexities were localized by measuring regional blood oxygen level-dependent (BOLD) signal intensity and volumes of activation using functional magnetic resonance imaging (fMRI). Some studies have shown that sequential finger movements recruit discrete sets of brain areas with different functions. To investigate the differential characteristics of the functional connectivity of brain networks produced by sequential movements of different complexities, we compared the temporal cross-correlation coefficients of each pair of brain regions within related neural systems among 14 subjects. Experimental results generally indicated an increased functional connectivity in relative brain areas during the performance of heterogeneous (complex) sequential finger movements compared to repetitive (simple) sequential finger movements. This finding showed that these areas are more selectively related to sequence performance. The results provide quantitative support for using a graphic method to investigate the descending pathway through which information is transmitted within complex sequences. Our findings highlight obvious differences in the functional organization of brain areas associated with complex and simple sequences. These discrepancies that might ref