电针结合重复经颅磁刺激对焦虑和抑郁障碍共病患者情绪认知功能影响的研究-针灸推拿专业论文.pdf.docxVIP

ABSTRACTObjective:To exploretheeffectofemotionalcognitivefunction.of EA combined with repetitive transcranialmagnetic stimulation(rTMS) onCAD patients .Methods:NinetycasesofCADwererandomizedintothreegroups.30casesin observationgroupweretreatedwithelectroacupuncturecombinedwithrTMS(EA group).30casesincontrolgroupweretreatedwithsimplerTMS.another30casesin controlgropweretreatedwithsimplepharmacotherapy.andanother30nomalcases asnormalcontrol.Separately,beforetreatment,5daysand10daysaftertreatment, HemiltonDepressionScale(HAMD)andHemiltonAnxietyScale(HAMA)were usedfor thescoringof depression andanxiety. Additionally,theefficacieswere comparedthrough threegroups.90 CAD casesand30health volunteerswererecruited Eventrelatedpotentials(ERP),suchasP300,MMN,P50,CNV,wereappliedtorecorderthe change ofemotionalcognitionbefore and 10 days aftertreatment．Results:1.5daysand10daysaftertreatment,HAMDandHAMAscoreinEA groupwaslowerthanthatinrTMSgroupandmedicinegroup(P0.001).and5days aftertreatment,rTMSgroupwaslowerthanthatinmedicinegroup.10daysafter treatmentHAMDscoreinrTMSgroupwaslowerthanthatinmedicinegroup.2.The remarkableeffectiveratesofdepressionandanxietyinEA group5daysafter treatmentwere56.7%(17/30)and66.7%(20/30)respectively,whichwerehigher apparentlythan30%(9/30)and26.7%(8/30)inrTMSgroup,andhigherthan11.1% (3/27)and 11.1%(3/27)inmedicinegroupseparately (P0.05).The remarkable effectiveratesofdepressionandanxietyinEAgroup10daysaftertreatmentwere 90%(27/30)respectively,whichwerehigherapparentlythan63.3%(19/30)inrTMS group,andhigherthan57.9%(14/27)inmedicinegroupseparately(P0.05).3.the MMNlatency in EAgroup beforetreatment was longerthan that normal group（P0.05）,butthedifferencefromthenomalgroupdisappearedaftertreatment (P0.05).therewassignificantdifferencebetweenbeforetreatmentandaftertreantmentinEA group. （P0.001）.MMN latencyinrTMS groupwas lowerthan thatnormalgroup（P0.05）.MMNlatencyinmedicinegroupbeforeandaftertreatmentwaslongerthanthatnormalgroup（P0.05）,andnosignificantd