基于代谢组学评价中药对ccl4致肝损伤药效-evaluating the efficacy of traditional chinese medicine on liver injury caused by ccl 4 based on metabolomics.docxVIP

目录引言...................................................................................................................11 代谢组学概述...................................................................................................12 代谢组学与其他组学的关系............................................................................23代谢组学研究方法...........................................................................................23.1研究样本来源........................................................................................33.2 样本制备................................................................................................33.3样本检测技术........................................................................................33.4数据分析处理技术................................................................................53.5生物标记物的发现................................................................................64 肝损伤动物模型的研究概况............................................................................64.1化学性肝损伤........................................................................................74.2免疫性肝损伤........................................................................................84.3酒精性肝损伤........................................................................................94.4其他肝损伤............................................................................................95基于代谢组学技术的中药治疗肝损伤的研究现状.......................................96本文研究目标与内容...................................................................................10第一章CCl4肝损伤模型的构建及中药干预作用..................................................111 实验材料与仪器.............................................................................................111.1试剂与耗材...........................................................................................111.2 仪器......................................................................................................121.3 动物...................................................