(内分泌系统）endocrinephysiology-I知识介绍.pptVIP

thyroid hormone epinephrine + thyroid hormone epinephrine no small amount large amount Hormones given Adipocyte Amount of fatty acids released Competitive action（竞争作用） Circadian rhythm of cortisol secretion pulsatile release 1. Biorhythm Ⅳ. Regulation of hormone secretion circadian rhythm 昼夜时间 血浆激素水平的脉冲式和日周期性变化 2. Effectors action on hormone levels （直接反馈调节） Endocrine gland St. Hormone Target tissues Response + - + + - - parathyroid gland PTH kidney bone [Ca2+] ↑ + + - [Ca2+] 3. Influence of other hormones hypothalamus-adenohypophysis-target gland axes Long- loop - - Short- loop - Hypothalamus Adenohypophysis Target gland Hormone + + - Ultrashort-loop - CNS negative feedback Hypothalamus Adenohypophysis ovary estradiol LH GnRH + + Positive feedback ovulation 排卵前后雌激素对高位激素分泌的反馈调节 下丘脑-腺垂体-甲状腺轴 下丘脑-腺垂体-肾上腺轴 下丘脑-腺垂体-性腺轴 hypothalamus-adenohypophysis-target gland axes 下丘脑—腺垂体—甲状腺轴 下丘脑—腺垂体—肾上腺皮质轴 下丘脑—腺垂体—性腺轴 hypothalamus-adenohypophysis-thyroid axes hypothalamus-adenohypophysis-adrenal cortex axes hypothalamus-adenohypophysis-gonad axes 下丘脑—腺垂体—靶腺轴 神经支配 交感神经支配：甲状腺腺泡 肾上腺髓质 肾近球小体 胰岛A细胞 迷走神经支配： 胰岛B细胞 双重神经支配：胃肠道内分泌细胞 4. Regulation by nervous system ANS adrenal medulla + hormone endocrine gland + or - autonomic ganglion hormone + adeno -hypophysis hypothalamus . . . target gland . . . hypothalamus integrates endocrine system with nerve centers Innervation Summary Definition of endocrine system and hormorne 内分泌系统和激素的概念 Transport modes of hormones 激素的转运方式 Characteristics of hormone action 激素作用的一般特征 Regulation of hormone secretion 激素分泌的调节 Part 2 Neuroendocrinology Neuroendocrine system hypothalamus hypophysis neurohypophsis adenohypophysis Hypothalamus-neurohypophysis system Hypothalamus—adenohypophysis system (antidiuretic hormone, ADH) Ⅰ. Hypothalamus-neurohypophysis system hypothalamohypophyseal tract