脊椎椎体ct值与骨密度值相关性实验及临床分析-experimental and clinical analysis of correlation between ct value and bmd value of vertebral body.docx

万方数据 万方数据 值呈明显正相关。② 动物实验中扫描条件为 120 kV、200mAs 时 CT 值与 BMD 值的相关系数最高。③ 120kV、200mAs 扫描条件下的腹部常规 CT 检查可用于 成年人腰椎椎体骨质密度测量并对骨质疏松程度判断，当成年人腰椎椎体 CT 值 介于 96HU~145HU 时，认为诊断椎体低骨量的准确性是最高的，当腰椎椎体 CT 值≤96HU 时，认为诊断椎体骨质疏松的准确性是最高的，当腰椎椎体 CT 值≥ 145HU 时，认为诊断椎体骨质正常骨量的准确性是最高的。 【关键词】电子计算机断层扫描仪；定量CT；骨质疏松；BMD值；CT值 The Correlation of CT Value and Bone Mineral Density Value III on Spinal Vertebral in Experiment and Clinical Research Major: Radiation medicine Postgraduate: Chai Xin Supervisor: Professor Jiao Jun Associate Professor: Duan Qinghong [Abstract] Objective: Explore the relations of CT value and Quantitative CT Bone Mineral Density value in cancellous Bone of vitro animal vertebral body model with different scan settings, evaluation by CT value to judge the diagnosis range of the adults vertebral bone mass in normal bone mass、low bone mass and osteoporosis. Methods: ① By means of self-made in vitro animal vertebral body model in different CT scans, analysis of different CT scans to measurement and the relationship of CT value and BMD value. The CT scan(200mAs,120kV) has the highest correlation coefficient of CT value and BMD value .② Using the highest correlation coefficient scanning conditions of CT value and BMD value in animal experiments, collected the subjects of different ages and genders for a total of 300 cases. Selected L1-3 vertebral cancellous bone as the measuring object, region of interest (ROI) in the vertebral body central cancellous bone area and avoid the bone cortex or vertebral vein. Adjusted the ROI size and shape, ROI area about 100mm2， depth about 7mm. Using SPSS 19.0 to analysis the differences and correlation between the vertebral bodies. With BMD values for the diagnosis of osteoporosis as the gold standard (BMD value is less than 80mg/cm3, diagnosis of osteoporosis; When the BMD value of 80~120mg/cm3, diagnosis of bone loss; When the BMD values greater than 120mg/cm3, diagnosis of normal bone mass), Using ROC curve area to conclusion CT values of the corresp