长托宁对妊娠期高血压剖宫产围术期心血管系统稳定作用.docVIP

长托宁对妊娠期高血压剖宫产围术期心血管系统稳定作用 　　摘 要 目的：观察麻醉前用长托宁对妊娠期高血压剖宫产围术期心血管系统是否有稳定作用。方法：妊娠期高血压拟行剖宫产患者60例，随机分为3组，A组术前静注长托宁0.5mg，B组术前静注东莨菪碱0.3mg(均配成5ml溶液)，C组静注生理盐水5ml。记录注药前即刻、注药后5分钟、手术开始时、手术结束时、术毕2小时、术毕4小时共6个时点的HR、BP的值以及3组术中需加用麻黄碱的病例数。结果：A组术中血压、心率变化缓和，术后回升缓慢，无显著性差异(P＞0.05)；B组心率升高明显，血压始终维持在较高水平；C组术中血压、心率变化明显，有显著性差异(P＜0.05)；A组、B组需加用麻黄碱的病例数少，和C组比较有显著性差异(P＜0.05)。结论：长托宁对妊娠期高血压剖宫产围术期心血管系统有稳定作用。 　　摘 要 目的：观察麻醉前用长托宁对妊娠期高血压剖宫产围术期心血管系统是否有稳定作用。方法：妊娠期高血压拟行剖宫产患者60例，随机分为3组，A组术前静注长托宁0.5mg，B组术前静注东莨菪碱0.3mg(均配成5ml溶液)，C组静注生理盐水5ml。记录注药前即刻、注药后5分钟、手术开始时、手术结束时、术毕2小时、术毕4小时共6个时点的HR、BP的值以及3组术中需加用麻黄碱的病例数。结果：A组术中血压、心率变化缓和，术后回升缓慢，无显著性差异(P＞0.05)；B组心率升高明显，血压始终维持在较高水平；C组术中血压、心率变化明显，有显著性差异(P＜0.05)；A组、B组需加用麻黄碱的病例数少，和C组比较有显著性差异(P＜0.05)。结论：长托宁对妊娠期高血压剖宫产围术期心血管系统有稳定作用。 　　关键词 长托宁 妊娠期高血压 围术期 心血管 稳定作用 　　关键词 长托宁 妊娠期高血压 围术期 心血管 稳定作用 　　doi:10.3969/j.issn.1007-614x.2012.05.174 　　doi:10.3969/j.issn.1007-614x.2012.05.174 　　Abstract Objective:To study pre-operative Penehyclidine Hydrochioride’s stabilization on the cardiovascular system during cesarean section for gestational hypertension parturient.Methods:60 cases of selective cesarean section gestational hypertension parturient were randomly assigned to three groups,A group,received Penehyclidine Hydrochioride 0.5mg iv;B group,received scopolamine 0.3mg iv;C group,received the saline 5ml iv.The heart rate and blood pressure were recorded when give medicine immediately before、give medicine after five minutes、at the first of surgery、at the end of surgery、surgery finish two hours、surgery finish four hours.The cases of using Ephedrine were recorded too.Results:There was not significant difference in the heart rate and blood pressure at different time points in A group(P＞0.05)and there was significant difference in B and C group(P＜0.05);There was significant difference in the cases of using Ephedrine between A，B and C guoups(P＜0.05).Conclusion:There are stabilization on the cardiovascular system during cesarean section for gestational hypertension parturient when Penehyclidine