成都地区女性四季节唇红部皮肤生理状况研究.docVIP

成都地区女性四季节唇红部皮肤生理状况研究 　　[摘要]目的：观察年龄和季节对唇部干燥度和老化的影响。方法：将56名年龄20～50岁的成都地区女性在签署知情同意书后入组，分为高、低年龄组，分别在秋、冬、春、夏四季节观察唇红部皮肤的干燥度、细纹、鳞屑、皲裂、弹性、饱满度及光泽度。结果：两年龄组唇红部干燥度、细纹、鳞屑有显著差别(P＜0.05)，高龄组比低龄组严重；弹性和光泽度低龄组显著好于高龄组(P＜0.05)；皲裂、饱满度两年龄组无差别(P＞0.05)。低龄组唇部皮肤的干燥度、细纹、鳞屑及弹性评分均随着季节而改变(P＜0.05)，高龄组唇部皮肤的临床评价，干燥度、鳞屑、皲裂及饱满度评分均随着季节而改变(P＜0.05)。两组均在冬季最为严重。结论：本研究提示不同季节、不同年龄的唇部干燥、唇部老化参数会发生改变，图谱法在唇部临床评价中是可行的。 　　[关键词]唇红；干燥；老化；图谱 　　[中图分类号]R751 [文献标识码]A [文章编号]1008-6455（2012）03-0442-04 　　 　　Four-season study on the condition of vermilion border of the lip among females living in Chengdu 　　ZHANG Lei1, ZHANG Zhi-ming2, WANG Xi1, WANG Si-yu1, LI Zhao-xia3, LI Li1 　　（1.Department of Dermatovenereology，West China Hospital，Sichuan University，Chengdu 610041，Sichuan,China; 　　2. LOréal Research and Innovation;3. Cosmetics Engineering Research Center in Sichuan） 　　 　　Abstract: Objective To observe age and seasonal effect on the lip physiological condition, such as dryness and aging. Methods 56 healthy female volunteers, aged 20～50, were recruited in Chengdu after signing informed consent form. They were split into two matched age groups: younger group included 27 women 20～35 y.o; older group included 28 women 36-50 y.o. The vermilion border of lip was assessed by clinical evaluation over the sequential four seasons. Evaluation parameters included overall dryness, fine lines, flakiness, chapping, elasticity, plumping and gloss. Results There were significant differences between the two age groups in clinical grading scores of overall dryness, fine lines, flakiness(P0.05) between the two age groups. In the younger age group, lip skin dryness, fine lines, flakiness and elasticity scores changed with the seasons (P 　　 试验前3天，不能使用任何唇部护理及彩妆产品。试验前30min禁止饮水、进食及吸烟等影响评价结果的行为。评价过程在同一照明环境下进行，保持环境的相对稳定，避免声音等干扰因素。 　　1.3 统计学方法：利用SPSS16.0统计软件包进行统计学分析，组间比较采用方差分析和秩和检验进行分析。P＜0.05 具有统计学差异。 　　2 结果 　　2.1年龄对唇部生理参数的影响：本次试验共入组60例志愿者，按照20～35岁年龄段及35～50岁年龄段分为低龄组和高龄组，各30例。试验期间失访4例，共完成56例，其中低龄组27例，年龄（27.19±4.09）岁，高龄组29例