类风湿性关节炎症状量化等级评判标准研究.docVIP

类风湿性关节炎症状量化等级评判标准研究 　　摘 要：类风湿性关节炎是常见病和多发病，致残率高，中医治疗有较好的疗效，虽取得了可喜的成绩，因无科学的中医疗效评定标准，致使在一定程度上影响了研究结论的真实性。因此制定中医药治疗类风湿性关节炎的疗效标准是当务之急。要制定本病的证候量化标准，首先需建立症状程度分级标准，依此标准进行病例调研，才能使建立的证候量化标准与临床实际相符，从而指导临床实际。因此症状半定量研究是证候量化的基础。对类风湿性关节炎常见症状，包括肢体、关节、肌肉、筋骨的症状与部分全身症状，进行半定量研究，制定出轻度、中度、重度的评分细则。 　　关键词：类风湿性关节炎；症状量化；评判标准 　　中图分类号：R259.932.2 　　文献标识码：A文章编号：1673-7717（2008）05-0972-02 　　 　　Study of Juding Criterion of Symptomatic Quantization Grade for Reumatoid Arthritis(RA) 　　ZHAO Xin?xiu?1，QIN Bing?2，YAN Yin?hu?3 　　 　　 (1Shanxi College of TCM,Taiyuan 030024,Shanxi,China;2.Xiangya Medical College,Central South University,Changsha 　　410008,Hunan,China;3.Rheumatoid Disease Hospital of Taiyuan,Taiyuan 030006,Shanxi,China) 　　Abstract:RA is a common and frequently encountered disease with high disability rate. TCM has good effect for RA,and has gotten delectable achievement, but because of no scientific juding criterion of effect in TCM,the truth of researching conclusion was influenced to a certain extent.Therefore, it is urent affairs to institute effect criterion for treating RA in TCM, and before doing this,firstly set down the grading criterion of symptomatic degree, according to which investigation and survey of cases can be gone along. Then symptomatic quantization established will be conincident with clinical fact, further direct clinical practice. Consequently, semiquantitative research of symptoms is the basis of syndromic quantization. The author carried through semiquantitative research of common symptoms of RA including symptoms on climbs, muscles, joints,tendons,bones and some general symptoms, and instituted grading fine points about mild, middle, severe degrees. 　　Keywords:Reumatoid Arthritis(RA);Symptomatic quantization;juding criterion 　　 　　辨证论治是中医的精髓，“证”是中医特有的诊断，在中医临床的???践中除了要对病进行诊断外，还须对“证进行定性及定量诊断。目前类风湿性关节炎(RA)临床疗效的判定多采用西医的疗效标准，缺少中医特色，制定中医药治疗类风湿性关节炎的疗效标准势在必行。虽然当前对证的定量研究，有各种先进方法，但是半定量研究是其前期工作和基础。只有对症状进行合理的分级，才能制定出符合实际的证候量化标准。2002年出版的《中药新药临床研究指导原则》虽然对类风湿性关节炎的症状进行了