新型席夫碱化合物的合成 表征及溶液配位化学分析-synthesis, characterization and solution coordination chemistry analysis of novel schiff base compounds.docxVIP

AbstractThestudiesbasedonSchiffbasearepaidmuchattentionduetothelargeflexibilityandgoodcoordinationcapabilityofSchiffbaseligand,speciallyit’snovelpropertiesshowedinbiochemistry,catalysis,electrochemistry,etc.Theworkofthispapermainlyincludesthreeaspects:SynthesisofchaintypecompoundsofSchiffbase:SynthesisofnewSchiffbasescontainingpyridinering.(5,5-(ethane-1,2-diylbis(oxy))bis(2-((pyridin-2-ylimino)methyl)phenol)and5,5-(hexane-1,6-diylbis(oxy))bis(2-((pyridin-2-ylimino)methyl)phenol))Theproductsobtainedarecharacterizedby1HNMR,FT-IRandthespectralpropertiesofSchiffbaseswerediscussed.Salenmacrocycliccompoundsweresynthesizedfromtheabovedialdehydesand(R,R)-1,2-diaminocyclo-hexane.Thenewmacrocycliccompoundswerechara-cterizedby1HNMR,FT-IR,UV-vis,elementalanalysesanalysisandthespectralpropertiesofSchiffbaseswerediscussed.NovelSchiffbasemacrocycliccompoundL5wassynthesizedfromresorcinanddiethylenetriaminebycondensationandcyclicaction.Theproductwascharacterizedby1HNMR,FT-IR,UV-vis,MS,andthespectralpropertiesofL5wasdiscussed.Thesing-crystalX-raystructuralanalysisrevealsthatfourionichydrogenbondsareobservedinthemacrocycliccompound.Themacrocycliccompoundhasasimilartoquadrilateralstructuralframework,andastrongintramolecularπ-πinteractionexistedbetweenthetwoparallelbenzenerings.ThecoordinationchemistryofL5andZn(Ⅱ)、Cu(Ⅱ)wereinvestigatedrespectively,usingtheUV-visspectrumtitrimetricmethod.Thethermodynamicpropertywasobtained.Keywords:Macrocylicschiffbase,Synthesis，Structurecharacterization，Characterization,Crystalstructure,CoordinationReaction第一章前言引言1864年，Schiff首次报道了伯胺与羰基化合物在一定条件下发生的缩合反应，生成具有甲亚胺基(azomethine)的产物R1R2C=NR3(R1,R2,R3分别为烷基,H,环己基,芳香基或杂环)，后人称之为Schiff碱(Schiffbase)（Schiff,H.1864)。迄今国内外学者仍在不断开展该领域的研究工作，特别是在其合成结构与应用等方面均不断有引人注目的进展。(M.A.shok,B.S.etal,2007)Schiff碱类化合物长期受到重视有其内在的因素。从Schiff碱的R1R2C=NR3结构组成的特征分析，R1,R2及R3均可被各种不同的基团取代，所以可以引入各类功能的基团；Schiff碱的核心结构是C=N-基团，N原子的杂化轨道上具有孤对电子，由此Schiff碱类化合物具有了重要的化学与生物学意义。Schiff碱类化合物可以灵活地选择反应物来制备，即通过取代基种类以及取代基位置的设计，合成出结构和性质丰富的Schiff碱化合物。同时，Schiff碱化合物作为配