两种丙泊酚配方在无痛人工流产术中应用比较.docVIP

两种丙泊酚配方在无痛人工流产术中应用比较 　　【摘要】 目的 比较单纯使用丙泊酚和丙泊酚复合小剂量芬太尼在无痛人工流产中的临床效果和安全性、经济性。方法 选择2007年7～10月自愿行无痛人工流产的患者156例，随机分为丙泊酚组（A组）和丙泊酚复合芬太尼组（B组）。B组于丙泊酚给药前予以芬太尼 1 μg/kg 缓慢静脉推注，两组患者丙泊酚的静脉推注剂量均为 2~2．5 mg/kg 。待麻醉效果满意后开始手术。结果 B组麻醉镇痛效果优75例，占96．1%；良3例，占3．9％；有效率为100%。A组麻醉镇痛效果优43例，占55．1%；良24例，占30．8%；差11例，占14．1%；有效率为 85．9％。两组之间比较差异有统计学意义(P 　　【关键词】 丙泊酚；芬太尼；人工流产；麻醉 　　 　　The comparative study of propofol anesthesia for induced abortion LI hong-mei Herbalist Hospital of Jiangbei, Chongqing 400020，China 　　【Abstract】 Objective To determine the clinical effects, security and economy of defferent propofol anesthesia for induced abortion. Methods 156 patients were randomly divided into group A and B, Group A was only provided with propofol for induced abortion and Group B combination with propofol and fentanyl. Each patient of group B received fentanyl 1 μg/kg intravenously before they were anesthetized with propofol. Afterwards each patient was anesthetized with propofol 2-2．5 mg/kg intravenously before the operation started. Each patient absorbed oxygen (2 L／min)in the operation. Results Among the group B,there are 75 cases of excellent anesthetic effects (96.1%) and 3 cases of nicer anesthetic effects (3．9%).The total valid rate is 100%. Among the group A,there are 43 cases of excellent anesthetic effects (55．1%) and 24 cases of nicer anesthetic effects 　　 (30．8%).The total valid rate is 85．9%.Conclusion Combination use of propofol with fentanyl intravenously for induced abortion, is better than only propofol anesthesia for induced abortion in security and economy. 　　【Key words】 Propofol ; Fentanyl ; Induced abortion ; Anesthesia 　　 　　麻醉技术引入人工流产术后，为术者提供了良好的施术条件，有效减少人流并发症。丙泊酚是一种起效快、时效短、苏醒快、可控易调的静脉全麻药品，成为门诊无痛人流首选静脉麻醉药。但因其镇痛作用较弱，目前提倡镇痛药复合应用，以提高麻醉效果。我院对单纯使用丙泊酚和丙泊酚复合小剂量芬太尼2种方法进行比较，现报告如下。 　　 　　1 资料与方法 　　 　　1．1 一般资料 选择门诊ASA1~2级自愿接受无痛人工流产手术的患者156例，随机分为单纯丙泊酚(A)组和丙泊酚复合小剂量芬太尼(B)组，每组78例。年龄18～38岁， 体质量42～68 kg，孕周5～8周，B超确诊为宫内妊娠，无严重心肺脑病史，无药物过敏史。 　　1．2 麻醉方法 术前禁饮食6 h以上，无术前用药。入室建立静脉通道后，监测并记录 MAP、RR