糖尿病足溃疡感染的抗生素治疗PPT课件.pptVIP

* Diabetic foot infections arise from the interaction of 3 main factors: neuropathy, angiopathy, and immunopathy.1 Neuropathy is the central element in the development of a diabetic foot infection. The loss of protective sensation leaves the foot vulnerable to ulceration associated with trauma, dry and cracked skin, or excessive pressure from abnormal foot anatomy and biomechanics (ie, clawing of toes, high arch, and subluxed metatarsophalangeal joints).2 The presence of ischemia is principally responsible for poor healing. As well, reduced blood perfusion inhibits supplies of oxygen, nutrie